Aberration in DNA methylation in B-cell lymphomas has a complex origin and increases with disease severity.

Aberration in DNA methylation in B-cell lymphomas has a complex origin and increases with disease severity.

Despite mounting evidence that epigenetic abnormalities play a key role in cancer biology, their contributions to the malignant phenotype remain poorly understood. Here we studied genome-wide DNA methylation in normal B-cell populations and subtypes of B-cell non-Hodgkin lymphoma: follicular lymphom...

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Main Authors: Subhajyoti De, Rita Shaknovich, Markus Riester, Olivier Elemento, Huimin Geng, Matthias Kormaksson, Yanwen Jiang, Bruce Woolcock, Nathalie Johnson, Jose M Polo, Leandro Cerchietti, Randy D Gascoyne, Ari Melnick, Franziska Michor
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1003137&type=printable
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