CardiLect: A combined cross‐species lectin histochemistry protocol for the automated analysis of cardiac remodelling

CardiLect: A combined cross‐species lectin histochemistry protocol for the automated analysis of cardiac remodelling

Abstract Background Cardiac remodelling, a crucial aspect of heart failure, is commonly investigated in preclinical models by quantifying cardiomyocyte cross‐sectional area (CSA) and microvascular density (MVD) via histological methods, such as immunohistochemistry. To achieve this, optimized protoc...

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Main Authors: Tamás G. Gergely, Tamás Kovács, Andrea Kovács, Viktória E. Tóth, Nabil V. Sayour, Gábor M. Mórotz, Csenger Kovácsházi, Gábor B. Brenner, Zsófia Onódi, Balázs Enyedi, Domokos Máthé, Przemyslaw Leszek, Zoltán Giricz, Péter Ferdinandy, Zoltán V. Varga
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:ESC Heart Failure
Subjects:
Heart failure
Cardiac remodelling
Immunohistochemistry
Lectin
Echocardiography
Transverse aortic constriction
Online Access:https://doi.org/10.1002/ehf2.15155
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