Bidirectional Relationship among Cognitive Function, Muscle Mass, and Grip Strength in Older Adults: the BUSAN Study
Background With the increasing number of older individuals, understanding the interplay among muscle strength, muscle mass, and cognitive functions in aging populations is important. This study aimed to investigate the relationships among muscle mass, muscle strength, and cognitive function among ol...
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Korea Geriatrics Society
2025-06-01
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| Series: | Annals of Geriatric Medicine and Research |
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| Online Access: | http://www.e-agmr.org/upload/pdf/agmr-24-0157.pdf |
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| author | Du-Ri Kim Jong-Hwan Park Ting-Fu Lai Myung-Jun Shin Tae Sik Goh Jung Sub Lee Eunsoo Moon Yeong-Ae Yang |
| author_facet | Du-Ri Kim Jong-Hwan Park Ting-Fu Lai Myung-Jun Shin Tae Sik Goh Jung Sub Lee Eunsoo Moon Yeong-Ae Yang |
| author_sort | Du-Ri Kim |
| collection | DOAJ |
| description | Background With the increasing number of older individuals, understanding the interplay among muscle strength, muscle mass, and cognitive functions in aging populations is important. This study aimed to investigate the relationships among muscle mass, muscle strength, and cognitive function among older adults, with a focus on understanding the bidirectional correlations among these factors. Methods A total of 335 participants aged ≥65 years were analyzed. Comprehensive assessments, including body composition measurements, cognitive function evaluations using the Korean version of Mini-Mental State Examination (K-MMSE), tablet-based cognitive tests, and grip strength measurements were conducted. Statistical analyses included Spearman correlation and binary logistic regression explore the relationships among muscle mass, grip strength, and cognitive function while adjusting for potential confounders. Results Significant correlations were observed among grip strength, lean and skeletal muscle mass index, and cognitive function. Lower grip strength was associated with lower K-MMSE scores, indicating a higher risk of cognitive decline. But lean and skeletal muscle masses index were not associated with cognitive decline. Further analysis revealed a bidirectional relationship, with cognitive decline being associated with reduced grip strength. Conclusion Maintaining muscle strength and mass are important potential strategies to support cognitive health in older individuals. These findings suggest a potential reciprocal relationship where better cognitive function may also contribute to the maintenance or improvement of grip strength. This interconnectedness highlights the importance of considering both physical and cognitive health in aging populations. |
| format | Article |
| id | doaj-art-940a2ccdf128420fb0ba02f651aca31e |
| institution | Kabale University |
| issn | 2508-4798 2508-4909 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Korea Geriatrics Society |
| record_format | Article |
| series | Annals of Geriatric Medicine and Research |
| spelling | doaj-art-940a2ccdf128420fb0ba02f651aca31e2025-08-20T03:29:10ZengKorea Geriatrics SocietyAnnals of Geriatric Medicine and Research2508-47982508-49092025-06-0129219920610.4235/agmr.24.01571188Bidirectional Relationship among Cognitive Function, Muscle Mass, and Grip Strength in Older Adults: the BUSAN StudyDu-Ri Kim0Jong-Hwan Park1Ting-Fu Lai2Myung-Jun Shin3Tae Sik Goh4Jung Sub Lee5Eunsoo Moon6Yeong-Ae Yang7 Biomedical Research Institute, Pusan National University Hospital, Busan, Korea Department of Convergence Medicine, Pusan National University School of Medicine, Yangsan, Korea Biomedical Research Institute, Pusan National University Hospital, Busan, Korea Biomedical Research Institute, Pusan National University Hospital, Busan, Korea Biomedical Research Institute, Pusan National University Hospital, Busan, Korea Biomedical Research Institute, Pusan National University Hospital, Busan, Korea Biomedical Research Institute, Pusan National University Hospital, Busan, Korea Department of Occupational Therapy, College of Biomedical Science and Engineering, Inje University, Gimhae, KoreaBackground With the increasing number of older individuals, understanding the interplay among muscle strength, muscle mass, and cognitive functions in aging populations is important. This study aimed to investigate the relationships among muscle mass, muscle strength, and cognitive function among older adults, with a focus on understanding the bidirectional correlations among these factors. Methods A total of 335 participants aged ≥65 years were analyzed. Comprehensive assessments, including body composition measurements, cognitive function evaluations using the Korean version of Mini-Mental State Examination (K-MMSE), tablet-based cognitive tests, and grip strength measurements were conducted. Statistical analyses included Spearman correlation and binary logistic regression explore the relationships among muscle mass, grip strength, and cognitive function while adjusting for potential confounders. Results Significant correlations were observed among grip strength, lean and skeletal muscle mass index, and cognitive function. Lower grip strength was associated with lower K-MMSE scores, indicating a higher risk of cognitive decline. But lean and skeletal muscle masses index were not associated with cognitive decline. Further analysis revealed a bidirectional relationship, with cognitive decline being associated with reduced grip strength. Conclusion Maintaining muscle strength and mass are important potential strategies to support cognitive health in older individuals. These findings suggest a potential reciprocal relationship where better cognitive function may also contribute to the maintenance or improvement of grip strength. This interconnectedness highlights the importance of considering both physical and cognitive health in aging populations.http://www.e-agmr.org/upload/pdf/agmr-24-0157.pdfsarcopeniacognitiongrip strengthmuscle strengthaged |
| spellingShingle | Du-Ri Kim Jong-Hwan Park Ting-Fu Lai Myung-Jun Shin Tae Sik Goh Jung Sub Lee Eunsoo Moon Yeong-Ae Yang Bidirectional Relationship among Cognitive Function, Muscle Mass, and Grip Strength in Older Adults: the BUSAN Study Annals of Geriatric Medicine and Research sarcopenia cognition grip strength muscle strength aged |
| title | Bidirectional Relationship among Cognitive Function, Muscle Mass, and Grip Strength in Older Adults: the BUSAN Study |
| title_full | Bidirectional Relationship among Cognitive Function, Muscle Mass, and Grip Strength in Older Adults: the BUSAN Study |
| title_fullStr | Bidirectional Relationship among Cognitive Function, Muscle Mass, and Grip Strength in Older Adults: the BUSAN Study |
| title_full_unstemmed | Bidirectional Relationship among Cognitive Function, Muscle Mass, and Grip Strength in Older Adults: the BUSAN Study |
| title_short | Bidirectional Relationship among Cognitive Function, Muscle Mass, and Grip Strength in Older Adults: the BUSAN Study |
| title_sort | bidirectional relationship among cognitive function muscle mass and grip strength in older adults the busan study |
| topic | sarcopenia cognition grip strength muscle strength aged |
| url | http://www.e-agmr.org/upload/pdf/agmr-24-0157.pdf |
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