Localized Relapse of Primary Plasma Cell Leukaemia in the Central Nervous System

Primary plasma cell leukaemia (pPCL) is a rare and aggressive form of plasma cell malignancies with a very poor prognosis. Compared to other plasma cell malignancies the tendency to extramedullary spread is increased; however central nervous system (CNS) involvement is rare and only reported in few...

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Main Authors: Christian W. Eskelund, Niels Frost Andersen
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2015/273565
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author Christian W. Eskelund
Niels Frost Andersen
author_facet Christian W. Eskelund
Niels Frost Andersen
author_sort Christian W. Eskelund
collection DOAJ
description Primary plasma cell leukaemia (pPCL) is a rare and aggressive form of plasma cell malignancies with a very poor prognosis. Compared to other plasma cell malignancies the tendency to extramedullary spread is increased; however central nervous system (CNS) involvement is rare and only reported in few cases. We report the case of a 61-year-old man who was diagnosed with pPCL and achieved a complete remission after autologous stem cell transplantation but had a relapse in the CNS without systemic disease.
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institution Kabale University
issn 2090-6560
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publishDate 2015-01-01
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series Case Reports in Hematology
spelling doaj-art-94075983dcfb44fc81d94bd5958abd762025-08-20T03:37:27ZengWileyCase Reports in Hematology2090-65602090-65792015-01-01201510.1155/2015/273565273565Localized Relapse of Primary Plasma Cell Leukaemia in the Central Nervous SystemChristian W. Eskelund0Niels Frost Andersen1Department of Haematology, Aarhus University Hospital, Aarhus, DenmarkDepartment of Haematology, Aarhus University Hospital, Aarhus, DenmarkPrimary plasma cell leukaemia (pPCL) is a rare and aggressive form of plasma cell malignancies with a very poor prognosis. Compared to other plasma cell malignancies the tendency to extramedullary spread is increased; however central nervous system (CNS) involvement is rare and only reported in few cases. We report the case of a 61-year-old man who was diagnosed with pPCL and achieved a complete remission after autologous stem cell transplantation but had a relapse in the CNS without systemic disease.http://dx.doi.org/10.1155/2015/273565
spellingShingle Christian W. Eskelund
Niels Frost Andersen
Localized Relapse of Primary Plasma Cell Leukaemia in the Central Nervous System
Case Reports in Hematology
title Localized Relapse of Primary Plasma Cell Leukaemia in the Central Nervous System
title_full Localized Relapse of Primary Plasma Cell Leukaemia in the Central Nervous System
title_fullStr Localized Relapse of Primary Plasma Cell Leukaemia in the Central Nervous System
title_full_unstemmed Localized Relapse of Primary Plasma Cell Leukaemia in the Central Nervous System
title_short Localized Relapse of Primary Plasma Cell Leukaemia in the Central Nervous System
title_sort localized relapse of primary plasma cell leukaemia in the central nervous system
url http://dx.doi.org/10.1155/2015/273565
work_keys_str_mv AT christianweskelund localizedrelapseofprimaryplasmacellleukaemiainthecentralnervoussystem
AT nielsfrostandersen localizedrelapseofprimaryplasmacellleukaemiainthecentralnervoussystem