Update on R-loops in genomic integrity: Formation, functions, and implications for human diseases
R-loops, three-strand nucleic acid structures, have emerged as crucial players in various physiological processes, including the regulation of gene expression, DNA replication, and class switch recombination. However, their presence also poses a significant threat to genome stability. A particularly...
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| Main Authors: | Min Zhu, Xinyu Wang, Hongchang Zhao, Zhenjie Wang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
KeAi Communications Co., Ltd.
2025-07-01
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| Series: | Genes and Diseases |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352304224001983 |
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