Aquaporin-4 triggers inflammation in a murine endotoxin-induced uveitis (EIU) model

Aquaporin-4 triggers inflammation in a murine endotoxin-induced uveitis (EIU) model

Abstract Introduction This study aimed to identify the role of aquaporin‑4 (AQP4) in uveitis, and screen for a novel therapeutic target of potential. Methods AQP4 knockout mice were applied in this study. The manifestations of mice oculi and inflammatory factors were monitored and compared between t...

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Main Authors: Qiang Wang, Yajun Gong, Xinqi Ma, Xin Fu, Ruobi Li, Kairui Qiu, Yanbin Wang, Qiulan Zhao, Ling Li, Qian Huang, Longyang Gao, Xiongli Hu, Xiaolai Zhou, Jingxiang Zhong
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Ophthalmology
Subjects:
Aquaporin‑4 (AQP4)
Endotoxin-induced uveitis (EIU)
Inflammation
Inflammatory factors
Online Access:https://doi.org/10.1186/s12886-025-04192-8
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