Coexistence of Chronic Lymphocytic Leukemia and Myeloproliferative Neoplasm

Chronic lymphocytic leukemia (CLL) is the most common adult leukemia in the Western world. Host immune surveillance caused mainly by the disease itself is speculated to be responsible for high incidence of secondary neoplasms. However, the simultaneous occurrence of CLL and myeloproliferative disord...

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Main Authors: Patrycja Zielinska, Miroslaw Markiewicz, Monika Dzierzak-Mietla, Anna Koclega, Grzegorz Helbig, Slawomira Kyrcz-Krzemien
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Case Reports in Oncological Medicine
Online Access:http://dx.doi.org/10.1155/2014/512928
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author Patrycja Zielinska
Miroslaw Markiewicz
Monika Dzierzak-Mietla
Anna Koclega
Grzegorz Helbig
Slawomira Kyrcz-Krzemien
author_facet Patrycja Zielinska
Miroslaw Markiewicz
Monika Dzierzak-Mietla
Anna Koclega
Grzegorz Helbig
Slawomira Kyrcz-Krzemien
author_sort Patrycja Zielinska
collection DOAJ
description Chronic lymphocytic leukemia (CLL) is the most common adult leukemia in the Western world. Host immune surveillance caused mainly by the disease itself is speculated to be responsible for high incidence of secondary neoplasms. However, the simultaneous occurrence of CLL and myeloproliferative disorder in the same patient is extremely rare. In the present report, a case of an 81-year-old man who was diagnosed with chronic lymphocytic leukemia and concomitant essential thrombocythemia is presented. We describe the morphologic, immunophenotypic, cytogenetic, and molecular findings in this patient. We also review the current literature.
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institution Kabale University
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publishDate 2014-01-01
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series Case Reports in Oncological Medicine
spelling doaj-art-93fd6c6ca35245039fe2a29d677732c02025-02-03T06:01:41ZengWileyCase Reports in Oncological Medicine2090-67062090-67142014-01-01201410.1155/2014/512928512928Coexistence of Chronic Lymphocytic Leukemia and Myeloproliferative NeoplasmPatrycja Zielinska0Miroslaw Markiewicz1Monika Dzierzak-Mietla2Anna Koclega3Grzegorz Helbig4Slawomira Kyrcz-Krzemien5Department of Hematology and Bone Marrow Transplantation, Medical University of Silesia, Dabrowskiego 25, 40-032 Katowice, PolandDepartment of Hematology and Bone Marrow Transplantation, Medical University of Silesia, Dabrowskiego 25, 40-032 Katowice, PolandDepartment of Hematology and Bone Marrow Transplantation, Medical University of Silesia, Dabrowskiego 25, 40-032 Katowice, PolandDepartment of Hematology and Bone Marrow Transplantation, Medical University of Silesia, Dabrowskiego 25, 40-032 Katowice, PolandDepartment of Hematology and Bone Marrow Transplantation, Medical University of Silesia, Dabrowskiego 25, 40-032 Katowice, PolandDepartment of Hematology and Bone Marrow Transplantation, Medical University of Silesia, Dabrowskiego 25, 40-032 Katowice, PolandChronic lymphocytic leukemia (CLL) is the most common adult leukemia in the Western world. Host immune surveillance caused mainly by the disease itself is speculated to be responsible for high incidence of secondary neoplasms. However, the simultaneous occurrence of CLL and myeloproliferative disorder in the same patient is extremely rare. In the present report, a case of an 81-year-old man who was diagnosed with chronic lymphocytic leukemia and concomitant essential thrombocythemia is presented. We describe the morphologic, immunophenotypic, cytogenetic, and molecular findings in this patient. We also review the current literature.http://dx.doi.org/10.1155/2014/512928
spellingShingle Patrycja Zielinska
Miroslaw Markiewicz
Monika Dzierzak-Mietla
Anna Koclega
Grzegorz Helbig
Slawomira Kyrcz-Krzemien
Coexistence of Chronic Lymphocytic Leukemia and Myeloproliferative Neoplasm
Case Reports in Oncological Medicine
title Coexistence of Chronic Lymphocytic Leukemia and Myeloproliferative Neoplasm
title_full Coexistence of Chronic Lymphocytic Leukemia and Myeloproliferative Neoplasm
title_fullStr Coexistence of Chronic Lymphocytic Leukemia and Myeloproliferative Neoplasm
title_full_unstemmed Coexistence of Chronic Lymphocytic Leukemia and Myeloproliferative Neoplasm
title_short Coexistence of Chronic Lymphocytic Leukemia and Myeloproliferative Neoplasm
title_sort coexistence of chronic lymphocytic leukemia and myeloproliferative neoplasm
url http://dx.doi.org/10.1155/2014/512928
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AT annakoclega coexistenceofchroniclymphocyticleukemiaandmyeloproliferativeneoplasm
AT grzegorzhelbig coexistenceofchroniclymphocyticleukemiaandmyeloproliferativeneoplasm
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