Liver failure diagnosis: key diagnostic biomarkers discovery and bioinformatic validation

Liver failure diagnosis: key diagnostic biomarkers discovery and bioinformatic validation

BackgroundGlutathione peroxidase 3 (GPX3) is a strong antioxidant. While elevated GPX3 levels are linked to diverse pathologies, its role in liver failure (LF) remains underexplored. This study investigates GPX3’s diagnostic potential and mechanistic contributions to LF pathogenesis.MethodsWe integr...

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Bibliographic Details
Main Authors: Quan Ye, Kai Wang, Hong Ye
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Genetics
Subjects:
glutathione peroxidase 3
hepatic failure
immune cell infiltration
promoter methylation
diagnostic biomarker
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2025.1554116/full
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