Targeting transforming growth factor-β1 by methylseleninic acid/seleno-L-methionine in clear cell renal cell carcinoma: Mechanisms and therapeutic potential

Targeting transforming growth factor-β1 by methylseleninic acid/seleno-L-methionine in clear cell renal cell carcinoma: Mechanisms and therapeutic potential

Clear cell renal cell carcinoma (ccRCC) poses a significant global health challenge as its incidence continues to rise, resulting in a substantial annual mortality rate. Major clinical challenges to current ccRCC treatments include high drug-resistance rates as well as dose-limiting adverse events;...

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Bibliographic Details
Main Authors: Aseel O. Rataan, Yan Xu, Sean M. Geary, Yousef Zakharia, Eman S. Kamel, Youcef M. Rustum, Aliasger K. Salem
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Cancer Treatment and Research Communications
Online Access:http://www.sciencedirect.com/science/article/pii/S2468294225000024
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