Adjuvants to the S1-subunit of the SARS-CoV-2 spike protein vaccine improve antibody and T cell responses and surrogate neutralization in mice

Adjuvants to the S1-subunit of the SARS-CoV-2 spike protein vaccine improve antibody and T cell responses and surrogate neutralization in mice

Abstract Various public health measures have contained outbreaks of SARS-CoV-2, but concerns remain over the possibility of future surges. Improvements in broadening the vaccine response can stifle new and nascent infections. In this study, we tested the effects of different adjuvant combinations on...

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Bibliographic Details
Main Authors: William Becker, Khadija Rebbani, Zhijian Duan, Eugene Valkov, Shawn Bryant, Mitchell Ho, Jay A. Berzofsky, Purevdorj B. Olkhanud
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
Vaccine
SARS-CoV-2
Adjuvants
Variants
Aging
Online Access:https://doi.org/10.1038/s41598-024-80636-3
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