Arrhythmia Detection in Atrioventricular, Single-Lead, Floating Atrial Dipole ICD Systems Compared with Conventional Single- and Dual-Chamber Defibrillators

Background: An atrioventricular defibrillator system with a floating atrial dipole (VDD ICD) can provide atrial sensing by a single lead. Our aim was to compare the arrhythmia detection efficacy of VDD ICDs with conventional single- (VVI) and dual-chamber (DDD) defibrillators. Methods: Data from con...

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Main Authors: Flora Diana Gausz, Kom Nangob Manuela Lena, Paul Emmanuel Gedeon, Marton Miklos, Attila Benak, Gabor Bencsik, Attila Makai, Dora Kranyak, Rita Beata Gagyi, Robert Pap, Laszlo Saghy, Tamas Szili-Torok, Mate Vamos
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Journal of Cardiovascular Development and Disease
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Online Access:https://www.mdpi.com/2308-3425/11/12/386
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author Flora Diana Gausz
Kom Nangob Manuela Lena
Paul Emmanuel Gedeon
Marton Miklos
Attila Benak
Gabor Bencsik
Attila Makai
Dora Kranyak
Rita Beata Gagyi
Robert Pap
Laszlo Saghy
Tamas Szili-Torok
Mate Vamos
author_facet Flora Diana Gausz
Kom Nangob Manuela Lena
Paul Emmanuel Gedeon
Marton Miklos
Attila Benak
Gabor Bencsik
Attila Makai
Dora Kranyak
Rita Beata Gagyi
Robert Pap
Laszlo Saghy
Tamas Szili-Torok
Mate Vamos
author_sort Flora Diana Gausz
collection DOAJ
description Background: An atrioventricular defibrillator system with a floating atrial dipole (VDD ICD) can provide atrial sensing by a single lead. Our aim was to compare the arrhythmia detection efficacy of VDD ICDs with conventional single- (VVI) and dual-chamber (DDD) defibrillators. Methods: Data from consecutive patients undergoing ICD implantation were retrospectively analyzed. The primary endpoint was the incidence of device-detected, new-onset atrial arrhythmias, while secondary endpoints were sensing parameters, complication rates, incidence of appropriate/inappropriate ICD therapy, arrhythmic/heart failure-related hospitalizations, and all-cause mortality. Results: A total of 256 patients (mean age 64 ± 12 years, male 75%, primary prophylaxis 28%, mean follow-up 3.7 ± 2.4 years) were included (VVI: 93, VDD: 94, DDD: 69). Atrial arrhythmia episodes were detected more frequently by VDD systems compared to VVI ICDs (aHR 7.087; 95% CI 2.371–21.183; <i>p</i> < 0.001), and at a rate similar to that of DDD ICDs (aHR 1.781; 95% CI 0.737–4.301; <i>p</i> = 0.200). The rate of inappropriate shocks was not different among the three ICD systems. Conclusion: VDD devices revealed an advantage in atrial arrhythmia detection compared to VVI ICDs and were non-inferior to DDD systems. Their main indication may be closer monitoring in high-risk patients with atrial arrhythmias to help therapy optimization and not the improvement of tachycardia discrimination.
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spelling doaj-art-93d76bd15e6a4e1c900993e2e64972662025-08-20T02:00:42ZengMDPI AGJournal of Cardiovascular Development and Disease2308-34252024-12-01111238610.3390/jcdd11120386Arrhythmia Detection in Atrioventricular, Single-Lead, Floating Atrial Dipole ICD Systems Compared with Conventional Single- and Dual-Chamber DefibrillatorsFlora Diana Gausz0Kom Nangob Manuela Lena1Paul Emmanuel Gedeon2Marton Miklos3Attila Benak4Gabor Bencsik5Attila Makai6Dora Kranyak7Rita Beata Gagyi8Robert Pap9Laszlo Saghy10Tamas Szili-Torok11Mate Vamos12Cardiac Electrophysiology Division, Cardiology Center, Department of Internal Medicine, University of Szeged, 6725 Szeged, HungaryCardiac Electrophysiology Division, Cardiology Center, Department of Internal Medicine, University of Szeged, 6725 Szeged, HungaryCardiac Electrophysiology Division, Cardiology Center, Department of Internal Medicine, University of Szeged, 6725 Szeged, HungaryCardiac Electrophysiology Division, Cardiology Center, Department of Internal Medicine, University of Szeged, 6725 Szeged, HungaryCardiac Electrophysiology Division, Cardiology Center, Department of Internal Medicine, University of Szeged, 6725 Szeged, HungaryCardiac Electrophysiology Division, Cardiology Center, Department of Internal Medicine, University of Szeged, 6725 Szeged, HungaryCardiac Electrophysiology Division, Cardiology Center, Department of Internal Medicine, University of Szeged, 6725 Szeged, HungaryCardiac Electrophysiology Division, Cardiology Center, Department of Internal Medicine, University of Szeged, 6725 Szeged, HungaryCardiac Electrophysiology Division, Cardiology Center, Department of Internal Medicine, University of Szeged, 6725 Szeged, HungaryCardiac Electrophysiology Division, Cardiology Center, Department of Internal Medicine, University of Szeged, 6725 Szeged, HungaryCardiac Electrophysiology Division, Cardiology Center, Department of Internal Medicine, University of Szeged, 6725 Szeged, HungaryCardiac Electrophysiology Division, Cardiology Center, Department of Internal Medicine, University of Szeged, 6725 Szeged, HungaryCardiac Electrophysiology Division, Cardiology Center, Department of Internal Medicine, University of Szeged, 6725 Szeged, HungaryBackground: An atrioventricular defibrillator system with a floating atrial dipole (VDD ICD) can provide atrial sensing by a single lead. Our aim was to compare the arrhythmia detection efficacy of VDD ICDs with conventional single- (VVI) and dual-chamber (DDD) defibrillators. Methods: Data from consecutive patients undergoing ICD implantation were retrospectively analyzed. The primary endpoint was the incidence of device-detected, new-onset atrial arrhythmias, while secondary endpoints were sensing parameters, complication rates, incidence of appropriate/inappropriate ICD therapy, arrhythmic/heart failure-related hospitalizations, and all-cause mortality. Results: A total of 256 patients (mean age 64 ± 12 years, male 75%, primary prophylaxis 28%, mean follow-up 3.7 ± 2.4 years) were included (VVI: 93, VDD: 94, DDD: 69). Atrial arrhythmia episodes were detected more frequently by VDD systems compared to VVI ICDs (aHR 7.087; 95% CI 2.371–21.183; <i>p</i> < 0.001), and at a rate similar to that of DDD ICDs (aHR 1.781; 95% CI 0.737–4.301; <i>p</i> = 0.200). The rate of inappropriate shocks was not different among the three ICD systems. Conclusion: VDD devices revealed an advantage in atrial arrhythmia detection compared to VVI ICDs and were non-inferior to DDD systems. Their main indication may be closer monitoring in high-risk patients with atrial arrhythmias to help therapy optimization and not the improvement of tachycardia discrimination.https://www.mdpi.com/2308-3425/11/12/386ICDimplantable cardioverter defibrillatorfloating atrial sensing dipoleVDDtachycardia discriminationatrial arrythmia detection
spellingShingle Flora Diana Gausz
Kom Nangob Manuela Lena
Paul Emmanuel Gedeon
Marton Miklos
Attila Benak
Gabor Bencsik
Attila Makai
Dora Kranyak
Rita Beata Gagyi
Robert Pap
Laszlo Saghy
Tamas Szili-Torok
Mate Vamos
Arrhythmia Detection in Atrioventricular, Single-Lead, Floating Atrial Dipole ICD Systems Compared with Conventional Single- and Dual-Chamber Defibrillators
Journal of Cardiovascular Development and Disease
ICD
implantable cardioverter defibrillator
floating atrial sensing dipole
VDD
tachycardia discrimination
atrial arrythmia detection
title Arrhythmia Detection in Atrioventricular, Single-Lead, Floating Atrial Dipole ICD Systems Compared with Conventional Single- and Dual-Chamber Defibrillators
title_full Arrhythmia Detection in Atrioventricular, Single-Lead, Floating Atrial Dipole ICD Systems Compared with Conventional Single- and Dual-Chamber Defibrillators
title_fullStr Arrhythmia Detection in Atrioventricular, Single-Lead, Floating Atrial Dipole ICD Systems Compared with Conventional Single- and Dual-Chamber Defibrillators
title_full_unstemmed Arrhythmia Detection in Atrioventricular, Single-Lead, Floating Atrial Dipole ICD Systems Compared with Conventional Single- and Dual-Chamber Defibrillators
title_short Arrhythmia Detection in Atrioventricular, Single-Lead, Floating Atrial Dipole ICD Systems Compared with Conventional Single- and Dual-Chamber Defibrillators
title_sort arrhythmia detection in atrioventricular single lead floating atrial dipole icd systems compared with conventional single and dual chamber defibrillators
topic ICD
implantable cardioverter defibrillator
floating atrial sensing dipole
VDD
tachycardia discrimination
atrial arrythmia detection
url https://www.mdpi.com/2308-3425/11/12/386
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