Effect of ABCG2 c.421 C> A (rs2231142) single nucleotide polymorphisms on the lipid-modulating efficacy of rosuvastatin: a meta-analysis

Effect of ABCG2 c.421 C> A (rs2231142) single nucleotide polymorphisms on the lipid-modulating efficacy of rosuvastatin: a meta-analysis

Abstract Background To systematically evaluate the effect of ABCG2 c.421 C > A (rs2231142) single nucleotide polymorphism (SNP) on the lipid-modulating efficacy of rosuvastatin (RST). Methods Searches were conducted using the Wan Fang database, Web of Science, Embase, PubMed, Cochrane Library, an...

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Bibliographic Details
Main Authors: Lingyan Liu, Yongkun Deng, Peng Li, Zhidan Zhang, Huiyou Li, Xingbiao Yang, Zhaoheng Yin, Yong Lai
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BMC Cardiovascular Disorders
Subjects:
ABCG2
BCRP
Rosuvastatin
Lipid-lowering efficacy
Single nucleotide polymorphisms
Online Access:https://doi.org/10.1186/s12872-025-04611-0
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