Formyl peptide receptor-1 (FPR1) represses intestinal oncogenesis

Formyl peptide receptor-1 (FPR1) represses intestinal oncogenesis

Formyl peptide receptor-1 (FPR1) is a pattern recognition receptor that is mostly expressed by myeloid cells. In patients with colorectal cancer (CRC), a loss-of-function polymorphism (rs867228) in the gene coding for FPR1 has been associated with reduced responses to chemotherapy or chemoradiothera...

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Bibliographic Details
Main Authors: Julie Le Naour, Léa Montégut, Yuhong Pan, Sarah Adriana Scuderi, Pierre Cordier, Adrien Joseph, Allan Sauvat, Valerio Iebba, Juliette Paillet, Gladys Ferrere, Ludivine Brechard, Claire Mulot, Grégory Dubourg, Laurence Zitvogel, Jonathan G. Pol, Erika Vacchelli, Pierre-Laurent Puig, Guido Kroemer
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:OncoImmunology
Subjects:
Bone marrow-derived dendritic cells
chemotaxis
immunogenic chemotherapy
immunosurveillance
tumor microenvironment
Online Access:https://www.tandfonline.com/doi/10.1080/2162402X.2023.2237354
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