Aurintricarboxylic acid inhibits the malignant phenotypes of drug-resistant cells via translation regulation

Genome instability, a hallmark of cancer, leads to endless mutations that eventually cause drug resistance against almost all chemotherapy drugs. This poses a significant obstacle to the success of cancer treatments. Here, we report that aurintricarboxylic acid (ATCA) effectively suppresses the mali...

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Bibliographic Details
Main Authors: Keke Shang, Yang Chen, Jingjie Jin, Tong Wang, Gong Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1576685/full
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