The Impact of Intermediate Antidrug Antibodies to Infliximab and Adalimumab on Clinical Outcomes in Patients with Crohn’s Disease or Ulcerative Colitis
Background: The anti-TNF drugs adalimumab (ADA) and infliximab (IFX) are effective treatments for inflammatory bowel disease (IBD). However, 40% of patients lose response, often due to the development of antibodies-to-ADA (ATA) and antibodies-to-IFX (ATI). While low ATA/ATI titres (<200 ng/mL) a...
Saved in:
| Main Authors: | Chaoyang Wang, Mazen Tolaymat, Raymond Cross |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
European Medical Journal
2022-03-01
|
| Series: | European Medical Journal |
| Online Access: | https://www.emjreviews.com/gastroenterology/article/the-impact-of-intermediate-antidrug-antibodies-to-infliximab-and-adalimumab-on-clinical-outcomes-in-patients-with-crohns-disease-or-ulcerative-colitis-j190121/ |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Granuloma annulare treated with certolizumab following the development of antidrug antibodies to adalimumab
by: Ayelet I. Rubenstein, BA, et al.
Published: (2025-07-01) -
Perinuclear antineutrophilic cytoplasmatic antibodies at patients with ulcerative colitis and Crohn’s disease
by: Ye. A. Konovich, et al.
Published: (2009-10-01) -
Predictors of infliximab efficacy in patients with severe attack of ulcerative colitis
by: A. O. Golovenko, et al.
Published: (2013-10-01) -
Infliximab-Induced Immune Thrombocytopenic Purpura in an Ulcerative Colitis Patient
by: Mark Lai, et al.
Published: (2025-06-01) -
The Use of Infliximab for Treatment of Hospitalized Patients with Acute Severe Ulcerative Colitis
by: B Bressler, et al.
Published: (2008-01-01)