Subjective Global Assessment and Handgrip Strength as Predictive Factors in Patients with Liver Cirrhosis
Background and Aims. Malnutrition is common in patients with chronic liver disease. We aimed to evaluate malnutrition assessment tools in predicting severity and survival of patients with liver cirrhosis. Material and Methods. We examined patients with liver cirrhosis. Nutritional evaluation was per...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2017/8348390 |
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| author | Maria Ciocîrlan Andreea Ruxandra Cazan Mihaela Barbu Mircea Mănuc Mircea Diculescu Mihai Ciocîrlan |
| author_facet | Maria Ciocîrlan Andreea Ruxandra Cazan Mihaela Barbu Mircea Mănuc Mircea Diculescu Mihai Ciocîrlan |
| author_sort | Maria Ciocîrlan |
| collection | DOAJ |
| description | Background and Aims. Malnutrition is common in patients with chronic liver disease. We aimed to evaluate malnutrition assessment tools in predicting severity and survival of patients with liver cirrhosis. Material and Methods. We examined patients with liver cirrhosis. Nutritional evaluation was performed on admission, using subjective global assessment (SGA), handgrip strength (HGS), and anthropometry. Patients were followed up for 6 months. Results. We included 100 patients, 72 men, with mean age of 59.2 years. According to disease severity, patients were 23% Child-Pugh A, 46% Child-Pugh B, and 31% Child-Pugh C. SGA and HGS significantly correlated with Child-Pugh, MELD, and MELD-Na scores on admission. At 6 months follow-up, 80.4% (78 of 97) of patients survived, while 3 patients were lost from observation. Survival was predicted by SGA (1 death in 32 patients SGA A, 8 deaths in 46 patients SGA B, and 9 deaths in 19 patients SGA C, p=0.001) and HGS (25.1 ± 8.5 in deceased versus 30.6 ± 10.9 in survivors, p=0.046). The mean BMI and MAMC values did not significantly differ between patients who survived or were deceased at 6 months. Conclusion. HGS and SGA may predict severity and short-term survival in cirrhotic patients. |
| format | Article |
| id | doaj-art-93a9b4b34dbb46f0997c7749d7ed3795 |
| institution | OA Journals |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-93a9b4b34dbb46f0997c7749d7ed37952025-08-20T02:10:10ZengWileyGastroenterology Research and Practice1687-61211687-630X2017-01-01201710.1155/2017/83483908348390Subjective Global Assessment and Handgrip Strength as Predictive Factors in Patients with Liver CirrhosisMaria Ciocîrlan0Andreea Ruxandra Cazan1Mihaela Barbu2Mircea Mănuc3Mircea Diculescu4Mihai Ciocîrlan5Gastroenterology Department, Fundeni Clinical Institute, Bucharest, RomaniaGastroenterology Department, Fundeni Clinical Institute, Bucharest, RomaniaGastroenterology Department, Fundeni Clinical Institute, Bucharest, RomaniaGastroenterology Department, Fundeni Clinical Institute, Bucharest, RomaniaGastroenterology Department, Fundeni Clinical Institute, Bucharest, Romania“Carol Davila” University of Medicine and Pharmacy, Bucharest, RomaniaBackground and Aims. Malnutrition is common in patients with chronic liver disease. We aimed to evaluate malnutrition assessment tools in predicting severity and survival of patients with liver cirrhosis. Material and Methods. We examined patients with liver cirrhosis. Nutritional evaluation was performed on admission, using subjective global assessment (SGA), handgrip strength (HGS), and anthropometry. Patients were followed up for 6 months. Results. We included 100 patients, 72 men, with mean age of 59.2 years. According to disease severity, patients were 23% Child-Pugh A, 46% Child-Pugh B, and 31% Child-Pugh C. SGA and HGS significantly correlated with Child-Pugh, MELD, and MELD-Na scores on admission. At 6 months follow-up, 80.4% (78 of 97) of patients survived, while 3 patients were lost from observation. Survival was predicted by SGA (1 death in 32 patients SGA A, 8 deaths in 46 patients SGA B, and 9 deaths in 19 patients SGA C, p=0.001) and HGS (25.1 ± 8.5 in deceased versus 30.6 ± 10.9 in survivors, p=0.046). The mean BMI and MAMC values did not significantly differ between patients who survived or were deceased at 6 months. Conclusion. HGS and SGA may predict severity and short-term survival in cirrhotic patients.http://dx.doi.org/10.1155/2017/8348390 |
| spellingShingle | Maria Ciocîrlan Andreea Ruxandra Cazan Mihaela Barbu Mircea Mănuc Mircea Diculescu Mihai Ciocîrlan Subjective Global Assessment and Handgrip Strength as Predictive Factors in Patients with Liver Cirrhosis Gastroenterology Research and Practice |
| title | Subjective Global Assessment and Handgrip Strength as Predictive Factors in Patients with Liver Cirrhosis |
| title_full | Subjective Global Assessment and Handgrip Strength as Predictive Factors in Patients with Liver Cirrhosis |
| title_fullStr | Subjective Global Assessment and Handgrip Strength as Predictive Factors in Patients with Liver Cirrhosis |
| title_full_unstemmed | Subjective Global Assessment and Handgrip Strength as Predictive Factors in Patients with Liver Cirrhosis |
| title_short | Subjective Global Assessment and Handgrip Strength as Predictive Factors in Patients with Liver Cirrhosis |
| title_sort | subjective global assessment and handgrip strength as predictive factors in patients with liver cirrhosis |
| url | http://dx.doi.org/10.1155/2017/8348390 |
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