Neurophysiological features in patients with migraine at risk for epilepsy

Objective: to study the electrophysiological parameters of brain bioelectric activity and features of the autonomous nervous system assessing heart rate variability, sympathetic skin response, clinical and physiological tests depending on the lateralization of migraine pain syndrome in the right or...

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Main Authors: N. D. Sorokina, A. V. Tsagashek, S. S. Pertsov, G. V. Selitsky, A. S. Zherdeva
Format: Article
Language:Russian
Published: IRBIS LLC 2021-10-01
Series:Эпилепсия и пароксизмальные состояния
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Online Access:https://www.epilepsia.su/jour/article/view/727
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author N. D. Sorokina
A. V. Tsagashek
S. S. Pertsov
G. V. Selitsky
A. S. Zherdeva
author_facet N. D. Sorokina
A. V. Tsagashek
S. S. Pertsov
G. V. Selitsky
A. S. Zherdeva
author_sort N. D. Sorokina
collection DOAJ
description Objective: to study the electrophysiological parameters of brain bioelectric activity and features of the autonomous nervous system assessing heart rate variability, sympathetic skin response, clinical and physiological tests depending on the lateralization of migraine pain syndrome in the right or left brain hemisphere in patients with epileptic electroencephalogram (EEG) signs and migraine.Material and methods. Thirty six patients with aura-free episodic migraine at risk of developing epilepsy and 9 age-matched healthy subjects were examined. All participants underwent EEG, clinical and physiological tests, assessment of heart rate variability and sympathetic skin response.Results. Patients with right-hemisphere migraine headache had signs of activated sympathetic nervous system at baseline level and during exercise, lower baseline EEG epileptiform activity and in provocative tests. In contrast to the subjects of this group, patients of other group featured with a more stable migraine pain syndrome in the left hemisphere tended to dominate with functional activity of the parasympathetic system such as increased trophotropic support during exercise, as well as greater magnitude of baseline epileptiform bioelectric activity and during load tests.Conclusion. Values of heart rate variability in combination with objective results of clinical and physiological assessment of the autonomous nervous system and electrophysiological parameters of brain bioelectric activity are reliable prognostic indicators for varying functional conditions in patients with episodic migraine.
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institution Kabale University
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2311-4088
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series Эпилепсия и пароксизмальные состояния
spelling doaj-art-939c7eee7beb435587269648aecff9a52025-08-20T03:39:32ZrusIRBIS LLCЭпилепсия и пароксизмальные состояния2077-83332311-40882021-10-0113322623610.17749/2077-8333/epi.par.con.2021.064547Neurophysiological features in patients with migraine at risk for epilepsyN. D. Sorokina0A. V. Tsagashek1S. S. Pertsov2G. V. Selitsky3A. S. Zherdeva4Yevdokimov Moscow State University of Medicine and DentistryYevdokimov Moscow State University of Medicine and Dentistry; Spasokukotskiy City Clinical HospitalYevdokimov Moscow State University of Medicine and Dentistry; Anokhin Research Institute of Normal PhysiologyYevdokimov Moscow State University of Medicine and DentistryYevdokimov Moscow State University of Medicine and DentistryObjective: to study the electrophysiological parameters of brain bioelectric activity and features of the autonomous nervous system assessing heart rate variability, sympathetic skin response, clinical and physiological tests depending on the lateralization of migraine pain syndrome in the right or left brain hemisphere in patients with epileptic electroencephalogram (EEG) signs and migraine.Material and methods. Thirty six patients with aura-free episodic migraine at risk of developing epilepsy and 9 age-matched healthy subjects were examined. All participants underwent EEG, clinical and physiological tests, assessment of heart rate variability and sympathetic skin response.Results. Patients with right-hemisphere migraine headache had signs of activated sympathetic nervous system at baseline level and during exercise, lower baseline EEG epileptiform activity and in provocative tests. In contrast to the subjects of this group, patients of other group featured with a more stable migraine pain syndrome in the left hemisphere tended to dominate with functional activity of the parasympathetic system such as increased trophotropic support during exercise, as well as greater magnitude of baseline epileptiform bioelectric activity and during load tests.Conclusion. Values of heart rate variability in combination with objective results of clinical and physiological assessment of the autonomous nervous system and electrophysiological parameters of brain bioelectric activity are reliable prognostic indicators for varying functional conditions in patients with episodic migraine.https://www.epilepsia.su/jour/article/view/727migraineepilepsyheart rate variabilitybioelectric brain activityautonomic nervous system
spellingShingle N. D. Sorokina
A. V. Tsagashek
S. S. Pertsov
G. V. Selitsky
A. S. Zherdeva
Neurophysiological features in patients with migraine at risk for epilepsy
Эпилепсия и пароксизмальные состояния
migraine
epilepsy
heart rate variability
bioelectric brain activity
autonomic nervous system
title Neurophysiological features in patients with migraine at risk for epilepsy
title_full Neurophysiological features in patients with migraine at risk for epilepsy
title_fullStr Neurophysiological features in patients with migraine at risk for epilepsy
title_full_unstemmed Neurophysiological features in patients with migraine at risk for epilepsy
title_short Neurophysiological features in patients with migraine at risk for epilepsy
title_sort neurophysiological features in patients with migraine at risk for epilepsy
topic migraine
epilepsy
heart rate variability
bioelectric brain activity
autonomic nervous system
url https://www.epilepsia.su/jour/article/view/727
work_keys_str_mv AT ndsorokina neurophysiologicalfeaturesinpatientswithmigraineatriskforepilepsy
AT avtsagashek neurophysiologicalfeaturesinpatientswithmigraineatriskforepilepsy
AT sspertsov neurophysiologicalfeaturesinpatientswithmigraineatriskforepilepsy
AT gvselitsky neurophysiologicalfeaturesinpatientswithmigraineatriskforepilepsy
AT aszherdeva neurophysiologicalfeaturesinpatientswithmigraineatriskforepilepsy