Integrated experimental and computational analysis reveals amoxicillin binding dynamics to PBP1a in Staphylococcus aureus

Integrated experimental and computational analysis reveals amoxicillin binding dynamics to PBP1a in Staphylococcus aureus

Abstract Methicillin-resistant Staphylococcus aureus (MRSA) represents a significant global health challenge due to acquired resistance mechanisms, primarily involving penicillin-binding protein 2a (PBP2a), necessitating novel therapeutic strategies. This study explores the potential of amoxicillin-...

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Bibliographic Details
Main Authors:	Seifeldin Elabed, Mariam Ali, Shrouk Hanafy, Sohila Mostafa, Momen Mamdouh, Ayman Meselhi
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-06-01
Series:	Scientific Reports
Online Access:	https://doi.org/10.1038/s41598-025-07626-x
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