Characterization and potential applications of silver nanoparticles: an insight on different mechanisms
In the 21st century, a great interest is devoted to biomedical application of various nanoparticles, particularly, as a means of improving the effectiveness of therapy for different diseases. Silver nanoparticles (AgNPs) are the most studied and investigated type of nanoparticles. Due to the wide sp...
Saved in:
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Ural Federal University
2022-07-01
|
| Series: | Chimica Techno Acta |
| Subjects: | |
| Online Access: | https://chimicatechnoacta.ru/article/view/5994 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850208660983119872 |
|---|---|
| author | Anton N. Kodintcev |
| author_facet | Anton N. Kodintcev |
| author_sort | Anton N. Kodintcev |
| collection | DOAJ |
| description | In the 21st century, a great interest is devoted to biomedical application of various nanoparticles, particularly, as a means of improving the effectiveness of therapy for different diseases. Silver nanoparticles (AgNPs) are the most studied and investigated type of nanoparticles. Due to the wide spectrum of their action, silver nanoparticles may be used both to influence pathogenic microorganisms and to improve the treatment of cancer. The basic physico-chemical characteristics and stabilizing agents play an important modifying role in the pharmacokinetics and pharmacodynamics of nanoparticles, determining the severity of the caused effect and their potential toxicity. This review summarizes the main physico-chemical properties of AgNPs and their impact on the biological effects. Additionally, biochemical and pathophysiological mechanisms of silver nanoparticles activity against various microorganisms and tumor cells are considered. Finally, we address the problems, associated with determining the optimal characteristics of nanoparticles, in order to increase their efficiency and reduce their toxicity for the macroorganism. |
| format | Article |
| id | doaj-art-9398c00b2a1d4e97a60d246c99dcdbc1 |
| institution | OA Journals |
| issn | 2411-1414 |
| language | English |
| publishDate | 2022-07-01 |
| publisher | Ural Federal University |
| record_format | Article |
| series | Chimica Techno Acta |
| spelling | doaj-art-9398c00b2a1d4e97a60d246c99dcdbc12025-08-20T02:10:12ZengUral Federal UniversityChimica Techno Acta2411-14142022-07-019410.15826/chimtech.2022.9.4.024494Characterization and potential applications of silver nanoparticles: an insight on different mechanismsAnton N. Kodintcev0Institute of High Temperature Electrochemistry, UB RASIn the 21st century, a great interest is devoted to biomedical application of various nanoparticles, particularly, as a means of improving the effectiveness of therapy for different diseases. Silver nanoparticles (AgNPs) are the most studied and investigated type of nanoparticles. Due to the wide spectrum of their action, silver nanoparticles may be used both to influence pathogenic microorganisms and to improve the treatment of cancer. The basic physico-chemical characteristics and stabilizing agents play an important modifying role in the pharmacokinetics and pharmacodynamics of nanoparticles, determining the severity of the caused effect and their potential toxicity. This review summarizes the main physico-chemical properties of AgNPs and their impact on the biological effects. Additionally, biochemical and pathophysiological mechanisms of silver nanoparticles activity against various microorganisms and tumor cells are considered. Finally, we address the problems, associated with determining the optimal characteristics of nanoparticles, in order to increase their efficiency and reduce their toxicity for the macroorganism.https://chimicatechnoacta.ru/article/view/5994silver nanoparticlesphysicochemical propertiesbiological effectstoxicity |
| spellingShingle | Anton N. Kodintcev Characterization and potential applications of silver nanoparticles: an insight on different mechanisms Chimica Techno Acta silver nanoparticles physicochemical properties biological effects toxicity |
| title | Characterization and potential applications of silver nanoparticles: an insight on different mechanisms |
| title_full | Characterization and potential applications of silver nanoparticles: an insight on different mechanisms |
| title_fullStr | Characterization and potential applications of silver nanoparticles: an insight on different mechanisms |
| title_full_unstemmed | Characterization and potential applications of silver nanoparticles: an insight on different mechanisms |
| title_short | Characterization and potential applications of silver nanoparticles: an insight on different mechanisms |
| title_sort | characterization and potential applications of silver nanoparticles an insight on different mechanisms |
| topic | silver nanoparticles physicochemical properties biological effects toxicity |
| url | https://chimicatechnoacta.ru/article/view/5994 |
| work_keys_str_mv | AT antonnkodintcev characterizationandpotentialapplicationsofsilvernanoparticlesaninsightondifferentmechanisms |