Silica-exposed patients with silicosis show shorter telomeres than do unexposed individuals: a pilot study in a population in southeastern Brazil

Silica-exposed patients with silicosis show shorter telomeres than do unexposed individuals: a pilot study in a population in southeastern Brazil

ABSTRACT Objective: Silicosis is a pneumoconiosis characterized by fibrosis of the lung parenchyma caused by the inhalation of silica particles. Silica dust inhalation is associated with inflammation and induction of oxidative stress in the lungs. This oxidative stress affects telomeres, which are...

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Bibliographic Details
Main Authors: Marcos César Santos de Castro, Lucas de Carvalho Costa, Kaio Cezar Rodrigues Salum, Hermano Albuquerque de Castro, Patrícia Canto Ribeiro, Walter Costa, Angela Santos Ferreira Nani, Fabiana Barzotto Kohlrausch
Format: Article
Language:English
Published: Sociedade Brasileira de Pneumologia e Tisiologia 2025-01-01
Series:Jornal Brasileiro de Pneumologia
Subjects:
Silicosis
Oxidative stress
Inflammation
Telomere
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-37132024000600605&lng=en&tlng=en
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