Seroprevalence of Immunoglobulins G and M Associated With Herpes Simplex Virus Type 2 among Apparently Healthy Individuals in Katsina State, Nigeria
Infection with Herpes Simplex Virus type 2 (HSV-2) is a significant public health problem being the leading cause of genital ulcerative disease. This study was aimed to evaluate the seroprevalence of herpes simplex virus type 2 among healthy individuals in Katsina State, and to determine the socio...
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| Format: | Article |
| Language: | English |
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Umaru Musa Yar'adua University, Katsina, Nigeria
2017-06-01
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| Series: | UMYU Journal of Microbiology Research |
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| Online Access: | https://ujmr.umyu.edu.ng/index.php/ujmr/article/view/311 |
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| author | Hayatudeen, M.R. Mukhtar, G.L. Aminu, M. |
| author_facet | Hayatudeen, M.R. Mukhtar, G.L. Aminu, M. |
| author_sort | Hayatudeen, M.R. |
| collection | DOAJ |
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Infection with Herpes Simplex Virus type 2 (HSV-2) is a significant public health problem being the leading cause of genital ulcerative disease. This study was aimed to evaluate the seroprevalence of herpes simplex virus type 2 among healthy individuals in Katsina State, and to determine the socio demographic and risk factors associated with HSV-2 infection in the study area. A cross-sectional serological survey enrolling 113 apparently healthy individuals from six Local Government Areas of Katsina State was conducted, to evaluate HSV-2 seroprevalence. Serum samples were obtained from randomly selected subjects. Samples were analysed using Immunoglobulins G (IgG) and M (IgM) HSV-2 specific commercial enzyme-linked immunosorbent assay kits. The overall seroprevalence of HSV-2 IgG and IgM was 71.7% and 32.7% respectively. HSV-2 seroprevalence increased with age. The results obtained demonstrated a high prevalence of HSV-2 seropositivity among apparently healthy individuals. We recommend educational awareness of Herpes type 2 infections among the populace and routine testing for Herpes type 2 antibodies in hospital laboratories to prevent HSV-2 related morbidity and mortality, particularly in apparently healthy individuals.
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| format | Article |
| id | doaj-art-938bf3afd57d42ed9bfcbf7a08e86982 |
| institution | OA Journals |
| issn | 2616-0668 2814-1822 |
| language | English |
| publishDate | 2017-06-01 |
| publisher | Umaru Musa Yar'adua University, Katsina, Nigeria |
| record_format | Article |
| series | UMYU Journal of Microbiology Research |
| spelling | doaj-art-938bf3afd57d42ed9bfcbf7a08e869822025-08-20T02:07:05ZengUmaru Musa Yar'adua University, Katsina, NigeriaUMYU Journal of Microbiology Research2616-06682814-18222017-06-012110.47430/ujmr.1721.027311Seroprevalence of Immunoglobulins G and M Associated With Herpes Simplex Virus Type 2 among Apparently Healthy Individuals in Katsina State, NigeriaHayatudeen, M.R.0Mukhtar, G.L.1Aminu, M.2Department of Microbiology, Umar Musa Yar’adua University, Katsina, Nigeria.Department of Microbiology, Umar Musa Yar’adua University, Katsina, Nigeria.Department of Microbiology, Ahmadu Bello University Zaria-Nigeria. Infection with Herpes Simplex Virus type 2 (HSV-2) is a significant public health problem being the leading cause of genital ulcerative disease. This study was aimed to evaluate the seroprevalence of herpes simplex virus type 2 among healthy individuals in Katsina State, and to determine the socio demographic and risk factors associated with HSV-2 infection in the study area. A cross-sectional serological survey enrolling 113 apparently healthy individuals from six Local Government Areas of Katsina State was conducted, to evaluate HSV-2 seroprevalence. Serum samples were obtained from randomly selected subjects. Samples were analysed using Immunoglobulins G (IgG) and M (IgM) HSV-2 specific commercial enzyme-linked immunosorbent assay kits. The overall seroprevalence of HSV-2 IgG and IgM was 71.7% and 32.7% respectively. HSV-2 seroprevalence increased with age. The results obtained demonstrated a high prevalence of HSV-2 seropositivity among apparently healthy individuals. We recommend educational awareness of Herpes type 2 infections among the populace and routine testing for Herpes type 2 antibodies in hospital laboratories to prevent HSV-2 related morbidity and mortality, particularly in apparently healthy individuals. https://ujmr.umyu.edu.ng/index.php/ujmr/article/view/311HSV-2SeroprevalenceIgGIgMKatsinaNigeria |
| spellingShingle | Hayatudeen, M.R. Mukhtar, G.L. Aminu, M. Seroprevalence of Immunoglobulins G and M Associated With Herpes Simplex Virus Type 2 among Apparently Healthy Individuals in Katsina State, Nigeria UMYU Journal of Microbiology Research HSV-2 Seroprevalence IgG IgM Katsina Nigeria |
| title | Seroprevalence of Immunoglobulins G and M Associated With Herpes Simplex Virus Type 2 among Apparently Healthy Individuals in Katsina State, Nigeria |
| title_full | Seroprevalence of Immunoglobulins G and M Associated With Herpes Simplex Virus Type 2 among Apparently Healthy Individuals in Katsina State, Nigeria |
| title_fullStr | Seroprevalence of Immunoglobulins G and M Associated With Herpes Simplex Virus Type 2 among Apparently Healthy Individuals in Katsina State, Nigeria |
| title_full_unstemmed | Seroprevalence of Immunoglobulins G and M Associated With Herpes Simplex Virus Type 2 among Apparently Healthy Individuals in Katsina State, Nigeria |
| title_short | Seroprevalence of Immunoglobulins G and M Associated With Herpes Simplex Virus Type 2 among Apparently Healthy Individuals in Katsina State, Nigeria |
| title_sort | seroprevalence of immunoglobulins g and m associated with herpes simplex virus type 2 among apparently healthy individuals in katsina state nigeria |
| topic | HSV-2 Seroprevalence IgG IgM Katsina Nigeria |
| url | https://ujmr.umyu.edu.ng/index.php/ujmr/article/view/311 |
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