A simple method of hiPSCs differentiation into insulin-producing cells is improved with vitamin C and RepSox.

Human induced pluripotent stem cells (hiPSCs) are considered a promising source of pancreatic β-cells for the treatment of diabetes. However, this approach is limited by issues such as low efficiency and high cost. Here, we have developed a new protocol to induce insulin-producing cells. To reduce c...

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Bibliographic Details
Main Authors: Ayumi Horikawa, Keiko Mizuno, Kyoko Tsuda, Takayoshi Yamamoto, Tatsuo Michiue
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0254373&type=printable
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