The chaperone BAG6 captures dislocated glycoproteins in the cytosol.

The chaperone BAG6 captures dislocated glycoproteins in the cytosol.

Secretory and membrane (glyco)proteins are subject to quality control in the endoplasmic reticulum (ER) to ensure that only functional proteins reach their destination. Proteins deemed terminally misfolded and hence functionally defective may be dislocated to the cytosol, where the proteasome degrad...

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Bibliographic Details
Main Authors: Jasper H L Claessen, Sumana Sanyal, Hidde L Ploegh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0090204&type=printable
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