Dead Space Ventilation Parallels Changes in Scintigraphic Vascular Obstruction at Recurrence of Pulmonary Embolism and after Thrombolytic Therapy: A Case Report

Physiological and alveolar dead space ventilation both increase in pulmonary embolism (PE) in proportion to the severity of vascular obstruction. The case of a patient with recurrent PE while on heparin therapy is presented. The recurrence was characterized clinically by severe pulmonary vascular ob...

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Main Authors: Marc A Rodger, Gwynne Jones, Francois Raymond, Daniel Lalonde, Mike Proulx, Lothar Huebsch, Christopher Bredeson
Format: Article
Language:English
Published: Wiley 1998-01-01
Series:Canadian Respiratory Journal
Online Access:http://dx.doi.org/10.1155/1998/539138
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author Marc A Rodger
Gwynne Jones
Francois Raymond
Daniel Lalonde
Mike Proulx
Lothar Huebsch
Christopher Bredeson
author_facet Marc A Rodger
Gwynne Jones
Francois Raymond
Daniel Lalonde
Mike Proulx
Lothar Huebsch
Christopher Bredeson
author_sort Marc A Rodger
collection DOAJ
description Physiological and alveolar dead space ventilation both increase in pulmonary embolism (PE) in proportion to the severity of vascular obstruction. The case of a patient with recurrent PE while on heparin therapy is presented. The recurrence was characterized clinically by severe pulmonary vascular obstruction and right heart dysfunction. The patient was treated with thrombolytic therapy, with excellent clinical and scintigraphic resolution. Dead space ventilation measurements at baseline, at the time of recurrence and after thrombolytic therapy are presented. The potential utility of dead space ventilation measurements for PE diagnosis and management are discussed.
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publishDate 1998-01-01
publisher Wiley
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series Canadian Respiratory Journal
spelling doaj-art-93828c2dc24b4409aa73bdac12e419c02025-08-20T03:37:20ZengWileyCanadian Respiratory Journal1198-22411998-01-015321521810.1155/1998/539138Dead Space Ventilation Parallels Changes in Scintigraphic Vascular Obstruction at Recurrence of Pulmonary Embolism and after Thrombolytic Therapy: A Case ReportMarc A Rodger0Gwynne Jones1Francois Raymond2Daniel Lalonde3Mike Proulx4Lothar Huebsch5Christopher Bredeson6Ottawa General Hospital, University of Ottawa, Ottawa, Ontario, CanadaOttawa General Hospital, University of Ottawa, Ottawa, Ontario, CanadaOttawa General Hospital, University of Ottawa, Ottawa, Ontario, CanadaOttawa General Hospital, University of Ottawa, Ottawa, Ontario, CanadaOttawa General Hospital, University of Ottawa, Ottawa, Ontario, CanadaOttawa General Hospital, University of Ottawa, Ottawa, Ontario, CanadaOttawa General Hospital, University of Ottawa, Ottawa, Ontario, CanadaPhysiological and alveolar dead space ventilation both increase in pulmonary embolism (PE) in proportion to the severity of vascular obstruction. The case of a patient with recurrent PE while on heparin therapy is presented. The recurrence was characterized clinically by severe pulmonary vascular obstruction and right heart dysfunction. The patient was treated with thrombolytic therapy, with excellent clinical and scintigraphic resolution. Dead space ventilation measurements at baseline, at the time of recurrence and after thrombolytic therapy are presented. The potential utility of dead space ventilation measurements for PE diagnosis and management are discussed.http://dx.doi.org/10.1155/1998/539138
spellingShingle Marc A Rodger
Gwynne Jones
Francois Raymond
Daniel Lalonde
Mike Proulx
Lothar Huebsch
Christopher Bredeson
Dead Space Ventilation Parallels Changes in Scintigraphic Vascular Obstruction at Recurrence of Pulmonary Embolism and after Thrombolytic Therapy: A Case Report
Canadian Respiratory Journal
title Dead Space Ventilation Parallels Changes in Scintigraphic Vascular Obstruction at Recurrence of Pulmonary Embolism and after Thrombolytic Therapy: A Case Report
title_full Dead Space Ventilation Parallels Changes in Scintigraphic Vascular Obstruction at Recurrence of Pulmonary Embolism and after Thrombolytic Therapy: A Case Report
title_fullStr Dead Space Ventilation Parallels Changes in Scintigraphic Vascular Obstruction at Recurrence of Pulmonary Embolism and after Thrombolytic Therapy: A Case Report
title_full_unstemmed Dead Space Ventilation Parallels Changes in Scintigraphic Vascular Obstruction at Recurrence of Pulmonary Embolism and after Thrombolytic Therapy: A Case Report
title_short Dead Space Ventilation Parallels Changes in Scintigraphic Vascular Obstruction at Recurrence of Pulmonary Embolism and after Thrombolytic Therapy: A Case Report
title_sort dead space ventilation parallels changes in scintigraphic vascular obstruction at recurrence of pulmonary embolism and after thrombolytic therapy a case report
url http://dx.doi.org/10.1155/1998/539138
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