Pentatrichomonas hominis induces extracellular traps formation of macrophages via the TLR2/NADPH/PAD4 pathway

Pentatrichomonas hominis induces extracellular traps formation of macrophages via the TLR2/NADPH/PAD4 pathway

Abstract Background Pentatrichomonas hominis (P. hominis) is a newly identified pathogenic zoonotic protozoan belonging to the Trichomonadidae family. P. hominis mainly parasitizes the cecum and colon of humans and other mammals, and it can cause diarrhea. Recently, macrophage extracellular traps (M...

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Bibliographic Details
Main Authors: Qi-an Zhai, Xi-chen Zhang, Hong-bo Zhang, Jian-hua Li, Peng-tao Gong, Xiao-cen Wang, Xin Li, Xu Zhang, Nan Zhang
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Parasites & Vectors
Subjects:
Pentatrichomonas hominis
Macrophage extracellular traps
TLR2
NADPH oxidase
PAD4
Online Access:https://doi.org/10.1186/s13071-025-06840-w
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