Current trends in the creation of cell-free allo- and xenotissues for reconstruction of heart structures

Tissue engineering has significant potential for solving the problems of durability of biological tissues when used in cardiac and vascular reconstructive surgery. A decellularization technology has been proposed for obtaining a biomaterial, morphologically and functionally similar to the damaged hu...

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Main Authors: S. I. Babenko, R. M. Muratov, M. N. Sorcomov
Format: Article
Language:Russian
Published: Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov 2021-04-01
Series:Вестник трансплантологии и искусственных органов
Subjects:
Online Access:https://journal.transpl.ru/vtio/article/view/1326
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author S. I. Babenko
R. M. Muratov
M. N. Sorcomov
author_facet S. I. Babenko
R. M. Muratov
M. N. Sorcomov
author_sort S. I. Babenko
collection DOAJ
description Tissue engineering has significant potential for solving the problems of durability of biological tissues when used in cardiac and vascular reconstructive surgery. A decellularization technology has been proposed for obtaining a biomaterial, morphologically and functionally similar to the damaged human heart tissue. This review discusses various aspects and models of biological tissue decellularization, including the modern technology of using supercritical carbon dioxide as the most eco-friendly and promising method.
format Article
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institution DOAJ
issn 1995-1191
language Russian
publishDate 2021-04-01
publisher Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov
record_format Article
series Вестник трансплантологии и искусственных органов
spelling doaj-art-9379c31cd7e34c6bbcae1d846271297e2025-08-20T03:01:37ZrusFederal Research Center of Transplantology and Artificial Organs named after V.I.ShumakovВестник трансплантологии и искусственных органов1995-11912021-04-0123115015610.15825/1995-1191-2021-1-150-156967Current trends in the creation of cell-free allo- and xenotissues for reconstruction of heart structuresS. I. Babenko0R. M. Muratov1M. N. Sorcomov2Bakulev National Medical Research Center for Cardiovascular SurgeryBakulev National Medical Research Center for Cardiovascular SurgeryBakulev National Medical Research Center for Cardiovascular SurgeryTissue engineering has significant potential for solving the problems of durability of biological tissues when used in cardiac and vascular reconstructive surgery. A decellularization technology has been proposed for obtaining a biomaterial, morphologically and functionally similar to the damaged human heart tissue. This review discusses various aspects and models of biological tissue decellularization, including the modern technology of using supercritical carbon dioxide as the most eco-friendly and promising method.https://journal.transpl.ru/vtio/article/view/1326heart valvetissue engineeringdecellularizationsupercritical carbon dioxide
spellingShingle S. I. Babenko
R. M. Muratov
M. N. Sorcomov
Current trends in the creation of cell-free allo- and xenotissues for reconstruction of heart structures
Вестник трансплантологии и искусственных органов
heart valve
tissue engineering
decellularization
supercritical carbon dioxide
title Current trends in the creation of cell-free allo- and xenotissues for reconstruction of heart structures
title_full Current trends in the creation of cell-free allo- and xenotissues for reconstruction of heart structures
title_fullStr Current trends in the creation of cell-free allo- and xenotissues for reconstruction of heart structures
title_full_unstemmed Current trends in the creation of cell-free allo- and xenotissues for reconstruction of heart structures
title_short Current trends in the creation of cell-free allo- and xenotissues for reconstruction of heart structures
title_sort current trends in the creation of cell free allo and xenotissues for reconstruction of heart structures
topic heart valve
tissue engineering
decellularization
supercritical carbon dioxide
url https://journal.transpl.ru/vtio/article/view/1326
work_keys_str_mv AT sibabenko currenttrendsinthecreationofcellfreealloandxenotissuesforreconstructionofheartstructures
AT rmmuratov currenttrendsinthecreationofcellfreealloandxenotissuesforreconstructionofheartstructures
AT mnsorcomov currenttrendsinthecreationofcellfreealloandxenotissuesforreconstructionofheartstructures