Robotic-assisted retroperitoneal lymph node dissection for stage II testicular cancer

Objective: To evaluate the perioperative as well as early oncological outcomes of patients undergoing robotic retroperitoneal lymph node dissection for treatment of testicular cancer. Methods: We conducted a prospective consecutive case series of patients undergoing robotic assisted retroperitoneal...

Full description

Saved in:
Bibliographic Details
Main Authors: George McClintock, Ahmed S. Goolam, Don Perera, Ryan Downey, Scott Leslie, Peter Grimison, Henry Woo, Peter Ferguson, Nariman Ahmadi
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Asian Journal of Urology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214388222000546
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849698556645998592
author George McClintock
Ahmed S. Goolam
Don Perera
Ryan Downey
Scott Leslie
Peter Grimison
Henry Woo
Peter Ferguson
Nariman Ahmadi
author_facet George McClintock
Ahmed S. Goolam
Don Perera
Ryan Downey
Scott Leslie
Peter Grimison
Henry Woo
Peter Ferguson
Nariman Ahmadi
author_sort George McClintock
collection DOAJ
description Objective: To evaluate the perioperative as well as early oncological outcomes of patients undergoing robotic retroperitoneal lymph node dissection for treatment of testicular cancer. Methods: We conducted a prospective consecutive case series of patients undergoing robotic assisted retroperitoneal lymph node dissection for metastatic testicular cancer between May 2018 and July 2021 at our institution. Data were collected on patient and tumour characteristics, intraoperative and postoperative parameters, and functional and oncological outcomes. Descriptive statistics are presented. Results: Nineteen patients were identified; 18 (94.7%) completed the procedure robotically and one was converted to open surgery; 78.9% of patients had stage ≥IIB and 12 (63.2%) patients had undergone prior chemotherapy. The median operative time was 300 (interquartile range [IQR] 240–315) min. Median blood loss was 100 (IQR 50–175) mL. Median length of stay was 2 (range 1–11) days. All robotically completed patients commenced diet and passed flatus on Day 1 and were discharged by Day 3. The median lymph node yield was 40.5 (IQR 38–51) nodes. All patients undergoing nerve-sparing procedures recovered antegrade ejaculatory function. One patient had a Clavien-Dindo III complication (chylous ascites requiring drainage). At a median follow-up of 22.3 (IQR 16.3–24.9) months, one patient developed retroperitoneal recurrence, which was successfully treated with second-line chemotherapy; no other patients have had recurrences. Conclusion: Robotic retroperitoneal lymph node dissection is a safe and feasible alternative to open surgery in appropriately selected patients, offering low morbidity. Early oncological outcomes are promising. Larger cohorts and longer follow-ups are required to validate our institution's findings.
format Article
id doaj-art-9371fd9fd60b47918435b4f8418889db
institution DOAJ
issn 2214-3882
language English
publishDate 2024-01-01
publisher Elsevier
record_format Article
series Asian Journal of Urology
spelling doaj-art-9371fd9fd60b47918435b4f8418889db2025-08-20T03:18:53ZengElsevierAsian Journal of Urology2214-38822024-01-0111112112710.1016/j.ajur.2022.03.010Robotic-assisted retroperitoneal lymph node dissection for stage II testicular cancerGeorge McClintock0Ahmed S. Goolam1Don Perera2Ryan Downey3Scott Leslie4Peter Grimison5Henry Woo6Peter Ferguson7Nariman Ahmadi8Department of Urology, Chris O'Brien Lifehouse, Sydney, NSW, Australia; Corresponding author.Department of Urology, Chris O'Brien Lifehouse, Sydney, NSW, AustraliaDepartment of Anaesthesia, Chris O'Brien Lifehouse, Sydney, NSW, AustraliaDepartment of Anaesthesia, Chris O'Brien Lifehouse, Sydney, NSW, AustraliaDepartment of Urology, Chris O'Brien Lifehouse, Sydney, NSW, Australia; The University of Sydney, Sydney, NSW, 2006, AustraliaThe University of Sydney, Sydney, NSW, 2006, Australia; Department of Medical Oncology, Chris O'Brien Lifehouse, Sydney, NSW, AustraliaDepartment of Urology, Chris O'Brien Lifehouse, Sydney, NSW, Australia; The University of Sydney, Sydney, NSW, 2006, AustraliaThe University of Sydney, Sydney, NSW, 2006, AustraliaDepartment of Urology, Chris O'Brien Lifehouse, Sydney, NSW, AustraliaObjective: To evaluate the perioperative as well as early oncological outcomes of patients undergoing robotic retroperitoneal lymph node dissection for treatment of testicular cancer. Methods: We conducted a prospective consecutive case series of patients undergoing robotic assisted retroperitoneal lymph node dissection for metastatic testicular cancer between May 2018 and July 2021 at our institution. Data were collected on patient and tumour characteristics, intraoperative and postoperative parameters, and functional and oncological outcomes. Descriptive statistics are presented. Results: Nineteen patients were identified; 18 (94.7%) completed the procedure robotically and one was converted to open surgery; 78.9% of patients had stage ≥IIB and 12 (63.2%) patients had undergone prior chemotherapy. The median operative time was 300 (interquartile range [IQR] 240–315) min. Median blood loss was 100 (IQR 50–175) mL. Median length of stay was 2 (range 1–11) days. All robotically completed patients commenced diet and passed flatus on Day 1 and were discharged by Day 3. The median lymph node yield was 40.5 (IQR 38–51) nodes. All patients undergoing nerve-sparing procedures recovered antegrade ejaculatory function. One patient had a Clavien-Dindo III complication (chylous ascites requiring drainage). At a median follow-up of 22.3 (IQR 16.3–24.9) months, one patient developed retroperitoneal recurrence, which was successfully treated with second-line chemotherapy; no other patients have had recurrences. Conclusion: Robotic retroperitoneal lymph node dissection is a safe and feasible alternative to open surgery in appropriately selected patients, offering low morbidity. Early oncological outcomes are promising. Larger cohorts and longer follow-ups are required to validate our institution's findings.http://www.sciencedirect.com/science/article/pii/S2214388222000546Retroperitoneal lymph node dissectionRobotic surgeryTesticular cancerRetroperitoneal node dissection
spellingShingle George McClintock
Ahmed S. Goolam
Don Perera
Ryan Downey
Scott Leslie
Peter Grimison
Henry Woo
Peter Ferguson
Nariman Ahmadi
Robotic-assisted retroperitoneal lymph node dissection for stage II testicular cancer
Asian Journal of Urology
Retroperitoneal lymph node dissection
Robotic surgery
Testicular cancer
Retroperitoneal node dissection
title Robotic-assisted retroperitoneal lymph node dissection for stage II testicular cancer
title_full Robotic-assisted retroperitoneal lymph node dissection for stage II testicular cancer
title_fullStr Robotic-assisted retroperitoneal lymph node dissection for stage II testicular cancer
title_full_unstemmed Robotic-assisted retroperitoneal lymph node dissection for stage II testicular cancer
title_short Robotic-assisted retroperitoneal lymph node dissection for stage II testicular cancer
title_sort robotic assisted retroperitoneal lymph node dissection for stage ii testicular cancer
topic Retroperitoneal lymph node dissection
Robotic surgery
Testicular cancer
Retroperitoneal node dissection
url http://www.sciencedirect.com/science/article/pii/S2214388222000546
work_keys_str_mv AT georgemcclintock roboticassistedretroperitoneallymphnodedissectionforstageiitesticularcancer
AT ahmedsgoolam roboticassistedretroperitoneallymphnodedissectionforstageiitesticularcancer
AT donperera roboticassistedretroperitoneallymphnodedissectionforstageiitesticularcancer
AT ryandowney roboticassistedretroperitoneallymphnodedissectionforstageiitesticularcancer
AT scottleslie roboticassistedretroperitoneallymphnodedissectionforstageiitesticularcancer
AT petergrimison roboticassistedretroperitoneallymphnodedissectionforstageiitesticularcancer
AT henrywoo roboticassistedretroperitoneallymphnodedissectionforstageiitesticularcancer
AT peterferguson roboticassistedretroperitoneallymphnodedissectionforstageiitesticularcancer
AT narimanahmadi roboticassistedretroperitoneallymphnodedissectionforstageiitesticularcancer