Kukoamine B regulates pyroptosis mediated by NLRP3/Caspase-1/GSDMD pathway to alleviate lipopolysaccharide-induced macrophage inflammation
Objective To investigate the regulatory effect of kukoamine B (KB) on the nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3)/Caspase-1/gasdermin D (GSDMD) pyroptosis pathway in human monocytic leukemia THP-1 cells induced by lipopolysaccharide (LPS). Methods THP-1 cells were i...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | zho |
| Published: |
Editorial Office of Journal of Guangxi Medical University
2024-07-01
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| Series: | Guangxi Yike Daxue xuebao |
| Subjects: | |
| Online Access: | https://journal.gxmu.edu.cn/article/doi/10.16190/j.cnki.45-1211/r.2024.07.010 |
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