Cadonilimab combined with trastuzumab and chemotherapy for HER2-positive gastric cancer with bone marrow metastasis and DIC: a case report and literature review

Cadonilimab combined with trastuzumab and chemotherapy for HER2-positive gastric cancer with bone marrow metastasis and DIC: a case report and literature review

BackgroundGastric cancer (GC) is one of the most common malignancies worldwide. While bone marrow metastasis (BMM) in GC is extremely rare and often complicated by disseminated intravascular coagulation (DIC), a critical condition with a median survival of less than three months in untreated patient...

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Bibliographic Details
Main Authors:	Meijing Chen, Jiwen Fan, Danyang Zhou, Boran Cheng, Shubin Wang, Gangling Tong
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-06-01
Series:	Frontiers in Immunology
Subjects:	gastric cancer (GC) bone marrow metastasis (BMM) disseminated intravascular coagulation (DIC) HER-2 PD-L1 immunotherapy
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1608636/full
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