Efficacy and safety of photobiomodulation combined with oral cryotherapy on oral mucosa pain in patients with burning mouth syndrome: a multi-institutional, randomized, controlled trial

Efficacy and safety of photobiomodulation combined with oral cryotherapy on oral mucosa pain in patients with burning mouth syndrome: a multi-institutional, randomized, controlled trial

Abstract Background The prevalence of burning mouth syndrome (BMS) is approximately 8% in clinical patients; thus, BMS remains a therapeutic challenge. Photobiomodulation (PBM) and oral cryotherapy (OCT) have been evaluated for the treatment of burning pain, but no confirmatory trials have been perf...

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Bibliographic Details
Main Authors: Chenghui Lu, Xuan Zhou, Chenglong Yang, Xinxiang Jiang, Xin Li, Zefan Huang, Qing Du, Guoyao Tang
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Medicine
Subjects:
Burning mouth syndrome
Photobiomodulation
Oral cryotherapy
Pain management
Oral health-related quality of life
Randomized clinical trial
Online Access:https://doi.org/10.1186/s12916-025-04015-z
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