Synovial Cysts of the Temporomandibular Joint: An Immunohistochemical Characterization and Literature Review

Synovial cysts of the temporomandibular joint (TMJ) are very rare, and to date, only 12 cases of a synovial cyst in the TMJ region have been reported in the literature. In this paper, we present the clinicopathological and immunohistochemical characteristics of one such lesion affecting a 48-year-...

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Main Authors: B. Vera-Sirera, J. A. Tomás-Amerigo, C. Baquero, F. J. Vera-Sempere
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Pathology
Online Access:http://dx.doi.org/10.1155/2013/508619
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author B. Vera-Sirera
J. A. Tomás-Amerigo
C. Baquero
F. J. Vera-Sempere
author_facet B. Vera-Sirera
J. A. Tomás-Amerigo
C. Baquero
F. J. Vera-Sempere
author_sort B. Vera-Sirera
collection DOAJ
description Synovial cysts of the temporomandibular joint (TMJ) are very rare, and to date, only 12 cases of a synovial cyst in the TMJ region have been reported in the literature. In this paper, we present the clinicopathological and immunohistochemical characteristics of one such lesion affecting a 48-year-old woman, presented with a mass in the left preauricular region. We describe the usefulness of immunohistochemical analysis for recognizing the synovial lining, which allowed for clear differentiation between ganglion and synovial cysts. Immunohistochemical analyses can be used to diagnose synovial cysts with certainty; however, using at least two markers is advisable to distinguish the two existing synovial cell subtypes. Our findings indicate that synovial cysts of TMJ possess an internal lining dominated by type B (fibroblast-like) synoviocytes.
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spelling doaj-art-9351734babd44cf4adc0361aba3e2ac82025-08-20T02:10:10ZengWileyCase Reports in Pathology2090-67812090-679X2013-01-01201310.1155/2013/508619508619Synovial Cysts of the Temporomandibular Joint: An Immunohistochemical Characterization and Literature ReviewB. Vera-Sirera0J. A. Tomás-Amerigo1C. Baquero2F. J. Vera-Sempere3Department of Stomatology, School of Medicine and Dentistry, University of Valencia, 46010 Valencia, SpainService of Maxillofacial Surgery, La Fe University Hospital, 46009 Valencia, SpainService of Maxillofacial Surgery, La Fe University Hospital, 46009 Valencia, SpainDepartment of Pathology, La Fe University Hospital and School of Medicine and Dentistry, University of Valencia, 46009 Valencia, SpainSynovial cysts of the temporomandibular joint (TMJ) are very rare, and to date, only 12 cases of a synovial cyst in the TMJ region have been reported in the literature. In this paper, we present the clinicopathological and immunohistochemical characteristics of one such lesion affecting a 48-year-old woman, presented with a mass in the left preauricular region. We describe the usefulness of immunohistochemical analysis for recognizing the synovial lining, which allowed for clear differentiation between ganglion and synovial cysts. Immunohistochemical analyses can be used to diagnose synovial cysts with certainty; however, using at least two markers is advisable to distinguish the two existing synovial cell subtypes. Our findings indicate that synovial cysts of TMJ possess an internal lining dominated by type B (fibroblast-like) synoviocytes.http://dx.doi.org/10.1155/2013/508619
spellingShingle B. Vera-Sirera
J. A. Tomás-Amerigo
C. Baquero
F. J. Vera-Sempere
Synovial Cysts of the Temporomandibular Joint: An Immunohistochemical Characterization and Literature Review
Case Reports in Pathology
title Synovial Cysts of the Temporomandibular Joint: An Immunohistochemical Characterization and Literature Review
title_full Synovial Cysts of the Temporomandibular Joint: An Immunohistochemical Characterization and Literature Review
title_fullStr Synovial Cysts of the Temporomandibular Joint: An Immunohistochemical Characterization and Literature Review
title_full_unstemmed Synovial Cysts of the Temporomandibular Joint: An Immunohistochemical Characterization and Literature Review
title_short Synovial Cysts of the Temporomandibular Joint: An Immunohistochemical Characterization and Literature Review
title_sort synovial cysts of the temporomandibular joint an immunohistochemical characterization and literature review
url http://dx.doi.org/10.1155/2013/508619
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