Bladder cancer diagnosis and identification of clinically significant disease by combined urinary detection of Mcm5 and nuclear matrix protein 22.

<h4>Background</h4>Urinary biomarkers for bladder cancer detection are constrained by inadequate sensitivity or specificity. Here we evaluate the diagnostic accuracy of Mcm5, a novel cell cycle biomarker of aberrant growth, alone and in combination with NMP22.<h4>Methods</h4>...

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Main Authors: John D Kelly, Tim J Dudderidge, Alex Wollenschlaeger, Odu Okoturo, Keith Burling, Fiona Tulloch, Ian Halsall, Teresa Prevost, Andrew Toby Prevost, Joana C Vasconcelos, Wendy Robson, Hing Y Leung, Nikhil Vasdev, Robert S Pickard, Gareth H Williams, Kai Stoeber
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0040305&type=printable
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