Staging of Laryngeal Cancer: Clinicoradiological versus Histopathological Findings using Modified Laryngeal Sectioning
INTRODUCTION: Laryngeal cancer is commonly encountered in India. Post operative whole organ sectioning of the larynx, although informative, can often be tedious and cumbersome. This study aims to define a modified method of laryngeal sectioning and to assess its level of agreement with pre-operativ...
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The Association of Otolaryngologists of India, West Bengal
2023-12-01
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| Series: | Bengal Journal of Otolaryngology and Head Neck Surgery |
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| Online Access: | https://bjohns.in/journal23/index.php/bjohns/article/view/31 |
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| author | Shriyash Sinha Sarmila Sen Somnath Saha |
| author_facet | Shriyash Sinha Sarmila Sen Somnath Saha |
| author_sort | Shriyash Sinha |
| collection | DOAJ |
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INTRODUCTION: Laryngeal cancer is commonly encountered in India. Post operative whole organ sectioning of the larynx, although informative, can often be tedious and cumbersome. This study aims to define a modified method of laryngeal sectioning and to assess its level of agreement with pre-operative clinicoradiological findings with regard to T-stage of laryngeal cancer.
METHODOLOGY: Prospective study was conducted on 15 patients diagnosed with laryngeal carcinoma, who underwent total laryngectomy with neck dissection. The pre-operative clinicoradiological T-stage, was compared to the post-operative pathological T-stage, obtained after histopathological examination of sections taken from relevant areas of the total laryngectomy specimen using modified laryngeal sectioning.
RESULTS: When compared to the pathological staging obtained after modified laryngeal sectioning, clinical T-staging over-staged the tumour in 3 cases and under-staged the tumour in 2 cases, and was similar in the remaining 10 cases. The level of agreement in determining the T-stage was ‘fair’.
CONCLUSION: The T-stages determined by pre-operative clinicoradiological findings and post-operative histopathological findings after modified laryngeal sectioning, were similar in two-third cases. While whole organ laryngeal sectioning remains the gold standard, it is often a costly and cumbersome process. We propose the use of representative tissue samples from the areas of interest for histopathological examination, obtained by sectioning the larynx at relevant points only, as it saves time and is less resource intensive.
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| format | Article |
| id | doaj-art-932921cdcc2b4a7d947dd8b53c86d6d2 |
| institution | Kabale University |
| issn | 2395-2393 2395-2407 |
| language | English |
| publishDate | 2023-12-01 |
| publisher | The Association of Otolaryngologists of India, West Bengal |
| record_format | Article |
| series | Bengal Journal of Otolaryngology and Head Neck Surgery |
| spelling | doaj-art-932921cdcc2b4a7d947dd8b53c86d6d22025-02-11T09:43:42ZengThe Association of Otolaryngologists of India, West BengalBengal Journal of Otolaryngology and Head Neck Surgery2395-23932395-24072023-12-0131210.47210/bjohns.2023.v31i2.767Staging of Laryngeal Cancer: Clinicoradiological versus Histopathological Findings using Modified Laryngeal SectioningShriyash Sinha0https://orcid.org/0000-0002-5124-5011Sarmila Sen1Somnath Saha2Calcutta National Medical College, 32, Gorachand Rd, Beniapukur, Kolkata, West Bengal - 700014Calcutta National Medical College, 32, Gorachand Rd, Beniapukur, Kolkata, West Bengal - 700014Calcutta National Medical College, 32, Gorachand Rd, Beniapukur, Kolkata, West Bengal - 700014 INTRODUCTION: Laryngeal cancer is commonly encountered in India. Post operative whole organ sectioning of the larynx, although informative, can often be tedious and cumbersome. This study aims to define a modified method of laryngeal sectioning and to assess its level of agreement with pre-operative clinicoradiological findings with regard to T-stage of laryngeal cancer. METHODOLOGY: Prospective study was conducted on 15 patients diagnosed with laryngeal carcinoma, who underwent total laryngectomy with neck dissection. The pre-operative clinicoradiological T-stage, was compared to the post-operative pathological T-stage, obtained after histopathological examination of sections taken from relevant areas of the total laryngectomy specimen using modified laryngeal sectioning. RESULTS: When compared to the pathological staging obtained after modified laryngeal sectioning, clinical T-staging over-staged the tumour in 3 cases and under-staged the tumour in 2 cases, and was similar in the remaining 10 cases. The level of agreement in determining the T-stage was ‘fair’. CONCLUSION: The T-stages determined by pre-operative clinicoradiological findings and post-operative histopathological findings after modified laryngeal sectioning, were similar in two-third cases. While whole organ laryngeal sectioning remains the gold standard, it is often a costly and cumbersome process. We propose the use of representative tissue samples from the areas of interest for histopathological examination, obtained by sectioning the larynx at relevant points only, as it saves time and is less resource intensive. https://bjohns.in/journal23/index.php/bjohns/article/view/31Laryngeal cancerclinical stagingradiological stagingpathological stagingwhole organ sectionmodified laryngeal sectioningRemove modified laryngeal sectioning |
| spellingShingle | Shriyash Sinha Sarmila Sen Somnath Saha Staging of Laryngeal Cancer: Clinicoradiological versus Histopathological Findings using Modified Laryngeal Sectioning Bengal Journal of Otolaryngology and Head Neck Surgery Laryngeal cancer clinical staging radiological staging pathological staging whole organ section modified laryngeal sectioningRemove modified laryngeal sectioning |
| title | Staging of Laryngeal Cancer: Clinicoradiological versus Histopathological Findings using Modified Laryngeal Sectioning |
| title_full | Staging of Laryngeal Cancer: Clinicoradiological versus Histopathological Findings using Modified Laryngeal Sectioning |
| title_fullStr | Staging of Laryngeal Cancer: Clinicoradiological versus Histopathological Findings using Modified Laryngeal Sectioning |
| title_full_unstemmed | Staging of Laryngeal Cancer: Clinicoradiological versus Histopathological Findings using Modified Laryngeal Sectioning |
| title_short | Staging of Laryngeal Cancer: Clinicoradiological versus Histopathological Findings using Modified Laryngeal Sectioning |
| title_sort | staging of laryngeal cancer clinicoradiological versus histopathological findings using modified laryngeal sectioning |
| topic | Laryngeal cancer clinical staging radiological staging pathological staging whole organ section modified laryngeal sectioningRemove modified laryngeal sectioning |
| url | https://bjohns.in/journal23/index.php/bjohns/article/view/31 |
| work_keys_str_mv | AT shriyashsinha stagingoflaryngealcancerclinicoradiologicalversushistopathologicalfindingsusingmodifiedlaryngealsectioning AT sarmilasen stagingoflaryngealcancerclinicoradiologicalversushistopathologicalfindingsusingmodifiedlaryngealsectioning AT somnathsaha stagingoflaryngealcancerclinicoradiologicalversushistopathologicalfindingsusingmodifiedlaryngealsectioning |