Acute transverse myelitis caused by Paragonimus infection: a case report and review of the literature
Acute transverse myelitis (ATM) is a rare but severe neurological disorder that can be triggered by infections, autoimmune conditions, or other factors. While the association between parasitic infections and ATM is uncommon, Paragonimus infection can cause significant neurological damage, posing a d...
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| Format: | Article |
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Frontiers Media S.A.
2025-05-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2025.1506201/full |
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| author | Zhiguo Wen Meiqiu Chen Cong Xia Yawei Sun Yifan Zhang Yifan Zhang |
| author_facet | Zhiguo Wen Meiqiu Chen Cong Xia Yawei Sun Yifan Zhang Yifan Zhang |
| author_sort | Zhiguo Wen |
| collection | DOAJ |
| description | Acute transverse myelitis (ATM) is a rare but severe neurological disorder that can be triggered by infections, autoimmune conditions, or other factors. While the association between parasitic infections and ATM is uncommon, Paragonimus infection can cause significant neurological damage, posing a diagnostic challenge. We report the case of a 65-year-old male patient who developed acute limb weakness, sensory loss, and fever following abdominal pain. Initial diagnostic tests were inconclusive; however, advanced imaging and metagenomic sequencing of cerebrospinal fluid ultimately confirmed an Paragonimus infection. After treatment with praziquantel, the patient successfully regained substantial motor function. This case highlights the need to consider parasitic infections in endemic areas and demonstrates the critical role of advanced diagnostic tools, such as metagenomic sequencing, in achieving timely diagnosis and treatment, ultimately improving the patient’s prognosis. |
| format | Article |
| id | doaj-art-931ada76e0154d6e8e53116a7936b15e |
| institution | OA Journals |
| issn | 2296-858X |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj-art-931ada76e0154d6e8e53116a7936b15e2025-08-20T02:27:13ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2025-05-011210.3389/fmed.2025.15062011506201Acute transverse myelitis caused by Paragonimus infection: a case report and review of the literatureZhiguo Wen0Meiqiu Chen1Cong Xia2Yawei Sun3Yifan Zhang4Yifan Zhang5School of Clinical Medicine, Guizhou Medical University, Guiyang, Guizhou, ChinaDepartment of Neurology, Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, ChinaDepartment of Neurology, Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, ChinaSchool of Clinical Medicine, Guizhou Medical University, Guiyang, Guizhou, ChinaSchool of Clinical Medicine, Guizhou Medical University, Guiyang, Guizhou, ChinaDepartment of Neurology, Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, ChinaAcute transverse myelitis (ATM) is a rare but severe neurological disorder that can be triggered by infections, autoimmune conditions, or other factors. While the association between parasitic infections and ATM is uncommon, Paragonimus infection can cause significant neurological damage, posing a diagnostic challenge. We report the case of a 65-year-old male patient who developed acute limb weakness, sensory loss, and fever following abdominal pain. Initial diagnostic tests were inconclusive; however, advanced imaging and metagenomic sequencing of cerebrospinal fluid ultimately confirmed an Paragonimus infection. After treatment with praziquantel, the patient successfully regained substantial motor function. This case highlights the need to consider parasitic infections in endemic areas and demonstrates the critical role of advanced diagnostic tools, such as metagenomic sequencing, in achieving timely diagnosis and treatment, ultimately improving the patient’s prognosis.https://www.frontiersin.org/articles/10.3389/fmed.2025.1506201/fullParagonimus heterotremusmyelitistransversemetagenomicsclinical featuresdiagnosis |
| spellingShingle | Zhiguo Wen Meiqiu Chen Cong Xia Yawei Sun Yifan Zhang Yifan Zhang Acute transverse myelitis caused by Paragonimus infection: a case report and review of the literature Frontiers in Medicine Paragonimus heterotremus myelitis transverse metagenomics clinical features diagnosis |
| title | Acute transverse myelitis caused by Paragonimus infection: a case report and review of the literature |
| title_full | Acute transverse myelitis caused by Paragonimus infection: a case report and review of the literature |
| title_fullStr | Acute transverse myelitis caused by Paragonimus infection: a case report and review of the literature |
| title_full_unstemmed | Acute transverse myelitis caused by Paragonimus infection: a case report and review of the literature |
| title_short | Acute transverse myelitis caused by Paragonimus infection: a case report and review of the literature |
| title_sort | acute transverse myelitis caused by paragonimus infection a case report and review of the literature |
| topic | Paragonimus heterotremus myelitis transverse metagenomics clinical features diagnosis |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2025.1506201/full |
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