Protective Role and Enhanced Intracellular Uptake of Curcumin in Retinal Cells Using Self-Emulsifying Drug Delivery Systems (SNEDDS)

Protective Role and Enhanced Intracellular Uptake of Curcumin in Retinal Cells Using Self-Emulsifying Drug Delivery Systems (SNEDDS)

<b>Background:</b> Sirtuin-1 (SIRT1), a histone deacetylase enzyme expressed in ocular tissues with intracellular localization, plays a critical protective role against various degenerative ocular diseases. The link between reduced SIRT1 levels and diabetic retinopathy (DR) has prompted...

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Bibliographic Details
Main Authors: Elide Zingale, Sebastiano Masuzzo, Tatu Lajunen, Mika Reinisalo, Jarkko Rautio, Valeria Consoli, Agata Grazia D’Amico, Luca Vanella, Rosario Pignatello
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Pharmaceuticals
Subjects:
ocular drug delivery
nanoemulsion
eye
retina
diabetic retinopathy
Sirtuin-1
Online Access:https://www.mdpi.com/1424-8247/18/2/265
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