Physiological regulation underlying the alleviation of cadmium stress in maize seedlings by exogenous glycerol

Abstract Cadmium (Cd) contamination in maize poses a significant threat to global food security due to its persistent accumulation in crops. In this study, the effects of foliar application of glycerol on Cd accumulation in maize seedlings were studied. Our results demonstrated that under Cd treatme...

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Main Authors: Qiao Li, Chunda Niu, Jiaxu Guo, Geng Chen, Jingti Li, Lei Sun, Wei Li, Tianpu Li
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-94385-4
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author Qiao Li
Chunda Niu
Jiaxu Guo
Geng Chen
Jingti Li
Lei Sun
Wei Li
Tianpu Li
author_facet Qiao Li
Chunda Niu
Jiaxu Guo
Geng Chen
Jingti Li
Lei Sun
Wei Li
Tianpu Li
author_sort Qiao Li
collection DOAJ
description Abstract Cadmium (Cd) contamination in maize poses a significant threat to global food security due to its persistent accumulation in crops. In this study, the effects of foliar application of glycerol on Cd accumulation in maize seedlings were studied. Our results demonstrated that under Cd treatment, biomass, total chlorophyll content, net photosynthetic rate (Pn), Ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO) activity, Phosphoenolpyruvate carboxylase (PEPC) activity, sucrose levels, and carbohydrate levels in maize seedlings significantly increased after glycerol application. H2O2 and MDA levels in both the aboveground and belowground portions of the maize plants significantly decreased. Moreover, superoxide dismutase (SOD), peroxidase (POD), and catalase (CAT) activities in the aboveground parts significantly increased. Notably, maize plants used glycerol to chelate Cd, which was fixed within the cell wall and soluble fraction of the roots, reducing Cd transport to the shoots and significantly lowering the Cd transport coefficient (TF). Transcriptomic data suggested that glycerol-mediated alleviation of Cd stress in maize seedlings may be associated with phenylpropanoid biosynthesis, plant-pathogen interactions and photosynthesis pathways. These molecular patterns align with the observed physiological improvements. This study provided a novel approach to effectively alleviate excessive Cd in maize and suggested possible applications of glycerol in cultivating plant resistance to heavy metals.
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spelling doaj-art-92f9bb8bbd4c47efacf7fbab9a72cc2c2025-08-20T01:54:23ZengNature PortfolioScientific Reports2045-23222025-04-0115111610.1038/s41598-025-94385-4Physiological regulation underlying the alleviation of cadmium stress in maize seedlings by exogenous glycerolQiao Li0Chunda Niu1Jiaxu Guo2Geng Chen3Jingti Li4Lei Sun5Wei Li6Tianpu Li7College of Agriculture, Northeast Agricultural UniversityCollege of Resources and Environment, Northeast Agricultural UniversityCollege of Resources and Environment, Northeast Agricultural UniversityCollege of Agriculture, Northeast Agricultural UniversityCollege of Resources and Environment, Northeast Agricultural UniversityCollege of Resources and Environment, Northeast Agricultural UniversityCollege of Agriculture, Northeast Agricultural UniversityCollege of Arts and Sciences, Northeast Agricultural UniversityAbstract Cadmium (Cd) contamination in maize poses a significant threat to global food security due to its persistent accumulation in crops. In this study, the effects of foliar application of glycerol on Cd accumulation in maize seedlings were studied. Our results demonstrated that under Cd treatment, biomass, total chlorophyll content, net photosynthetic rate (Pn), Ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO) activity, Phosphoenolpyruvate carboxylase (PEPC) activity, sucrose levels, and carbohydrate levels in maize seedlings significantly increased after glycerol application. H2O2 and MDA levels in both the aboveground and belowground portions of the maize plants significantly decreased. Moreover, superoxide dismutase (SOD), peroxidase (POD), and catalase (CAT) activities in the aboveground parts significantly increased. Notably, maize plants used glycerol to chelate Cd, which was fixed within the cell wall and soluble fraction of the roots, reducing Cd transport to the shoots and significantly lowering the Cd transport coefficient (TF). Transcriptomic data suggested that glycerol-mediated alleviation of Cd stress in maize seedlings may be associated with phenylpropanoid biosynthesis, plant-pathogen interactions and photosynthesis pathways. These molecular patterns align with the observed physiological improvements. This study provided a novel approach to effectively alleviate excessive Cd in maize and suggested possible applications of glycerol in cultivating plant resistance to heavy metals.https://doi.org/10.1038/s41598-025-94385-4MaizeCadmium stressGlycerolPhysiological characteristicsTranscriptome
spellingShingle Qiao Li
Chunda Niu
Jiaxu Guo
Geng Chen
Jingti Li
Lei Sun
Wei Li
Tianpu Li
Physiological regulation underlying the alleviation of cadmium stress in maize seedlings by exogenous glycerol
Scientific Reports
Maize
Cadmium stress
Glycerol
Physiological characteristics
Transcriptome
title Physiological regulation underlying the alleviation of cadmium stress in maize seedlings by exogenous glycerol
title_full Physiological regulation underlying the alleviation of cadmium stress in maize seedlings by exogenous glycerol
title_fullStr Physiological regulation underlying the alleviation of cadmium stress in maize seedlings by exogenous glycerol
title_full_unstemmed Physiological regulation underlying the alleviation of cadmium stress in maize seedlings by exogenous glycerol
title_short Physiological regulation underlying the alleviation of cadmium stress in maize seedlings by exogenous glycerol
title_sort physiological regulation underlying the alleviation of cadmium stress in maize seedlings by exogenous glycerol
topic Maize
Cadmium stress
Glycerol
Physiological characteristics
Transcriptome
url https://doi.org/10.1038/s41598-025-94385-4
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