Senegalin-2: A Novel Hexadecapeptide from <i>Kassina senegalensis</i> with Antibacterial and Muscle Relaxant Activities, and Its Derivative Senegalin-2BK as a Bradykinin Antagonist

Senegalin-2: A Novel Hexadecapeptide from <i>Kassina senegalensis</i> with Antibacterial and Muscle Relaxant Activities, and Its Derivative Senegalin-2BK as a Bradykinin Antagonist

The amphibian skin secretions are excellent sources of bioactive peptides, some of which and their derivatives exhibit multiple properties, including antibacterial and antagonism against bradykinin. A novel peptide Senegalin-2 was isolated from the skin secretions of <i>Kassina senegalensis<...

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Bibliographic Details
Main Authors: Yueyang Lu, Yanguo Zhu, Chengbang Ma, Lei Wang, Mei Zhou, Tianbao Chen, Xiaonan Ma, Xu Zhang, Zhimin Fan
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Biomolecules
Subjects:
amphibian
antimicrobial peptides
smooth muscle
bradykinin
antagonist
Online Access:https://www.mdpi.com/2218-273X/15/1/30
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