A tentative exploration for the association between influenza virus infection and SARS-CoV-2 infection in Shihezi, China: A test-negative study

The outbreak of respiratory diseases, such as COVID-19 and influenza, has drawn global attention. However, it remains unclear whether the risk of influenza A infection may be affected by the history of SARS-CoV-2 infection. In this study, we conducted a test-negative case-control study, and utilized...

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Main Authors: Songsong Xie, Yinxia Su, Yanji Zhao, Yaling Du, Zihao Guo, Xiu Gu, Jie Sun, Mohammad Javanbakht, Daihai He, Jiazhen Zhang, Yan Zhang, Kai Wang, Shi Zhao
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-03-01
Series:Infectious Disease Modelling
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Online Access:http://www.sciencedirect.com/science/article/pii/S2468042724001179
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author Songsong Xie
Yinxia Su
Yanji Zhao
Yaling Du
Zihao Guo
Xiu Gu
Jie Sun
Mohammad Javanbakht
Daihai He
Jiazhen Zhang
Yan Zhang
Kai Wang
Shi Zhao
author_facet Songsong Xie
Yinxia Su
Yanji Zhao
Yaling Du
Zihao Guo
Xiu Gu
Jie Sun
Mohammad Javanbakht
Daihai He
Jiazhen Zhang
Yan Zhang
Kai Wang
Shi Zhao
author_sort Songsong Xie
collection DOAJ
description The outbreak of respiratory diseases, such as COVID-19 and influenza, has drawn global attention. However, it remains unclear whether the risk of influenza A infection may be affected by the history of SARS-CoV-2 infection. In this study, we conducted a test-negative case-control study, and utilized a logistic regression model to analyze the relationship between SARS-CoV-2 and influenza A infections. Among 258 eligible patient samples with influenza-like illness (ILI), we did not detect a statistically significant association between the history of SARS-CoV-2 infection and the risk of influenza A infection. These findings might indicate that antibodies against COVID-19 acquired through vaccination or natural immunity have not protected against influenza.
format Article
id doaj-art-92e2b89cf3f8479cb1e755daf83b9474
institution OA Journals
issn 2468-0427
language English
publishDate 2025-03-01
publisher KeAi Communications Co., Ltd.
record_format Article
series Infectious Disease Modelling
spelling doaj-art-92e2b89cf3f8479cb1e755daf83b94742025-08-20T01:57:08ZengKeAi Communications Co., Ltd.Infectious Disease Modelling2468-04272025-03-0110120120610.1016/j.idm.2024.10.002A tentative exploration for the association between influenza virus infection and SARS-CoV-2 infection in Shihezi, China: A test-negative studySongsong Xie0Yinxia Su1Yanji Zhao2Yaling Du3Zihao Guo4Xiu Gu5Jie Sun6Mohammad Javanbakht7Daihai He8Jiazhen Zhang9Yan Zhang10Kai Wang11Shi Zhao12NHC Key Laboratory of Prevention and Treatment of Central Asia High Incidence Diseases, The First Affiliated Hospital of Shihezi University, Shihezi 832000, ChinaDepartment of Medical Engineering and Technology, Xinjiang Medical University, Urumqi 830017, ChinaDepartment of Applied Mathematics, Hong Kong Polytechnic University, Hong Kong, 999077, ChinaNHC Key Laboratory of Prevention and Treatment of Central Asia High Incidence Diseases, The First Affiliated Hospital of Shihezi University, Shihezi 832000, ChinaJC School of Public Health and Primary Care, Chinese University of Hong Kong, Hong Kong, 999077, ChinaSchool of Medicine, Shihezi University, Shihezi 832000, ChinaSchool of Computer Science, Hubei University of Technology, Wuhan 430068, ChinaNephrology and Urology Research Center, Baqiyatallah University of Medical Sciences, Tehran, IranDepartment of Applied Mathematics, Hong Kong Polytechnic University, Hong Kong, 999077, ChinaSchool of Medicine, Shihezi University, Shihezi 832000, ChinaSchool of Medicine, Shihezi University, Shihezi 832000, ChinaSchool of Public Health, Xinjiang Medical University, Urumqi, 830017, China; Corresponding author.School of Public Health, Tianjin Medical University, Tianjin, 300070, China; Corresponding author.The outbreak of respiratory diseases, such as COVID-19 and influenza, has drawn global attention. However, it remains unclear whether the risk of influenza A infection may be affected by the history of SARS-CoV-2 infection. In this study, we conducted a test-negative case-control study, and utilized a logistic regression model to analyze the relationship between SARS-CoV-2 and influenza A infections. Among 258 eligible patient samples with influenza-like illness (ILI), we did not detect a statistically significant association between the history of SARS-CoV-2 infection and the risk of influenza A infection. These findings might indicate that antibodies against COVID-19 acquired through vaccination or natural immunity have not protected against influenza.http://www.sciencedirect.com/science/article/pii/S2468042724001179Influenza ACOVID-19test-negative studyChina
spellingShingle Songsong Xie
Yinxia Su
Yanji Zhao
Yaling Du
Zihao Guo
Xiu Gu
Jie Sun
Mohammad Javanbakht
Daihai He
Jiazhen Zhang
Yan Zhang
Kai Wang
Shi Zhao
A tentative exploration for the association between influenza virus infection and SARS-CoV-2 infection in Shihezi, China: A test-negative study
Infectious Disease Modelling
Influenza A
COVID-19
test-negative study
China
title A tentative exploration for the association between influenza virus infection and SARS-CoV-2 infection in Shihezi, China: A test-negative study
title_full A tentative exploration for the association between influenza virus infection and SARS-CoV-2 infection in Shihezi, China: A test-negative study
title_fullStr A tentative exploration for the association between influenza virus infection and SARS-CoV-2 infection in Shihezi, China: A test-negative study
title_full_unstemmed A tentative exploration for the association between influenza virus infection and SARS-CoV-2 infection in Shihezi, China: A test-negative study
title_short A tentative exploration for the association between influenza virus infection and SARS-CoV-2 infection in Shihezi, China: A test-negative study
title_sort tentative exploration for the association between influenza virus infection and sars cov 2 infection in shihezi china a test negative study
topic Influenza A
COVID-19
test-negative study
China
url http://www.sciencedirect.com/science/article/pii/S2468042724001179
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