Nobiletin protected against hypertrophic cardiomyopathy via targeting PPARα

Nobiletin protected against hypertrophic cardiomyopathy via targeting PPARα

BackgroundHypertrophic cardiomyopathy is an independent risk factor for heart failure. Citrus reticulata (C. reticulata) is a traditional Chinese medicine with a variety of chemical components and pharmacological effects. The mechanisms of C. reticulata for treating hypertrophic cardiomyopathy are s...

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Bibliographic Details
Main Authors: Kewei Zhou, Chang Chen, Hexin Cai, Zuqian Lian, Luping Wang, Qinghuo Li, Cancan Wang, Xiaoqian Wu, Panxia Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Pharmacology
Subjects:
Citrus reticulata
hypertrophic cardiomyopathy
nobiletin
naringenin
PPARα
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1628625/full
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