The Role of the γδ T Cell in Allergic Diseases
The predominant distribution of γδ T cells in the mucosal and epithelial tissues makes these unconventional lymphocytes the “guards” to contact external environment (like allergens) and to contribute to immune surveillance, as well as “vanguards” to participate in initiating mucosal inflammation. Th...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2014-01-01
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| Series: | Journal of Immunology Research |
| Online Access: | http://dx.doi.org/10.1155/2014/963484 |
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| _version_ | 1849692766083219456 |
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| author | Rui Zheng Qintai Yang |
| author_facet | Rui Zheng Qintai Yang |
| author_sort | Rui Zheng |
| collection | DOAJ |
| description | The predominant distribution of γδ T cells in the mucosal and epithelial tissues makes these unconventional lymphocytes the “guards” to contact external environment (like allergens) and to contribute to immune surveillance, as well as “vanguards” to participate in initiating mucosal inflammation. Therefore, γδ T cells have been considered to bridge the innate and adaptive immunity. The role these cells play in allergy seems to be complicated and meaningful, so it makes sense to review the characteristics and role of γδ T cells in allergic diseases. |
| format | Article |
| id | doaj-art-92ced06e2c844ab68c8c284d22841201 |
| institution | DOAJ |
| issn | 2314-8861 2314-7156 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Immunology Research |
| spelling | doaj-art-92ced06e2c844ab68c8c284d228412012025-08-20T03:20:37ZengWileyJournal of Immunology Research2314-88612314-71562014-01-01201410.1155/2014/963484963484The Role of the γδ T Cell in Allergic DiseasesRui Zheng0Qintai Yang1Department of Otorhinolaryngology-Head and Neck Surgery, The Third Affiliated Hospital, SUN Yat-sen University, Guangzhou 510630, ChinaDepartment of Otorhinolaryngology-Head and Neck Surgery, The Third Affiliated Hospital, SUN Yat-sen University, Guangzhou 510630, ChinaThe predominant distribution of γδ T cells in the mucosal and epithelial tissues makes these unconventional lymphocytes the “guards” to contact external environment (like allergens) and to contribute to immune surveillance, as well as “vanguards” to participate in initiating mucosal inflammation. Therefore, γδ T cells have been considered to bridge the innate and adaptive immunity. The role these cells play in allergy seems to be complicated and meaningful, so it makes sense to review the characteristics and role of γδ T cells in allergic diseases.http://dx.doi.org/10.1155/2014/963484 |
| spellingShingle | Rui Zheng Qintai Yang The Role of the γδ T Cell in Allergic Diseases Journal of Immunology Research |
| title | The Role of the γδ T Cell in Allergic Diseases |
| title_full | The Role of the γδ T Cell in Allergic Diseases |
| title_fullStr | The Role of the γδ T Cell in Allergic Diseases |
| title_full_unstemmed | The Role of the γδ T Cell in Allergic Diseases |
| title_short | The Role of the γδ T Cell in Allergic Diseases |
| title_sort | role of the γδ t cell in allergic diseases |
| url | http://dx.doi.org/10.1155/2014/963484 |
| work_keys_str_mv | AT ruizheng theroleofthegdtcellinallergicdiseases AT qintaiyang theroleofthegdtcellinallergicdiseases AT ruizheng roleofthegdtcellinallergicdiseases AT qintaiyang roleofthegdtcellinallergicdiseases |