Purpose built catheters for minimally invasive surfactant therapy: Experience from a Canadian tertiary level neonatal intensive care unit
# Background Minimally invasive surfactant therapy (MIST), a method of surfactant delivery via a thin catheter during spontaneous breathing, is an increasingly popular alternative to intubation and surfactant administration. Recently, purpose-built catheters for MIST received regulatory approval in...
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| Format: | Article |
| Language: | English |
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Canadian Society of Respiratory Therapists
2023-06-01
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| Series: | Canadian Journal of Respiratory Therapy |
| Online Access: | https://doi.org/10.29390/001c.77606 |
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| author | Talib Al Harthy Michael R Miller Orlando daSilva Soume Bhattacharya |
| author_facet | Talib Al Harthy Michael R Miller Orlando daSilva Soume Bhattacharya |
| author_sort | Talib Al Harthy |
| collection | DOAJ |
| description | # Background
Minimally invasive surfactant therapy (MIST), a method of surfactant delivery via a thin catheter during spontaneous breathing, is an increasingly popular alternative to intubation and surfactant administration. Recently, purpose-built catheters for MIST received regulatory approval in Canada and became available for use. However, procedural success and user experience with such catheters have not been described.
# Methods
This retrospective cohort study included neonates who received MIST using purpose-built catheters between January 1, 2021, and March 31, 2022. Two types of purpose-built catheters were used in this period - SurfCath™ and BLEScath™. Procedural success, number of attempts, and adverse events in neonates receiving MIST via the two catheters were compared using chi-square or Fisher's tests. User experience was described using an ease-of-use scale.
# Results
Thirty-seven neonates met eligibility criteria; 22 received MIST via SurfCath™, whereas 15 received MIST via BLEScath™. Success rates were 91% in SurfCath™ and 93% in BLEScath™ (P\> 0.994). Failed attempts were lower in SurfCath™ (23%) in comparison to BLEScath™ (33%), but the difference was not statistically significant (P=0.708). Among operators, 90% found SurfCath™ very easy/relatively easy to use compared to 43% of users reflecting the same degree of use with BLEScath™ (P=.021). There was no difference in adverse events.
# Conclusion
This is the first study in Canada to report MIST with purpose-built catheters. Overall, the success rate was equally high with both catheters. Users subjectively reported higher ease of use with SurfCath™. Commercially available purpose-built catheters should facilitate universal adaptation of the MIST method. |
| format | Article |
| id | doaj-art-92ce6c6296a34d13a4d12c389556fbe2 |
| institution | Kabale University |
| issn | 2368-6820 |
| language | English |
| publishDate | 2023-06-01 |
| publisher | Canadian Society of Respiratory Therapists |
| record_format | Article |
| series | Canadian Journal of Respiratory Therapy |
| spelling | doaj-art-92ce6c6296a34d13a4d12c389556fbe22025-02-11T20:30:51ZengCanadian Society of Respiratory TherapistsCanadian Journal of Respiratory Therapy2368-68202023-06-0159Purpose built catheters for minimally invasive surfactant therapy: Experience from a Canadian tertiary level neonatal intensive care unitTalib Al HarthyMichael R MillerOrlando daSilvaSoume Bhattacharya# Background Minimally invasive surfactant therapy (MIST), a method of surfactant delivery via a thin catheter during spontaneous breathing, is an increasingly popular alternative to intubation and surfactant administration. Recently, purpose-built catheters for MIST received regulatory approval in Canada and became available for use. However, procedural success and user experience with such catheters have not been described. # Methods This retrospective cohort study included neonates who received MIST using purpose-built catheters between January 1, 2021, and March 31, 2022. Two types of purpose-built catheters were used in this period - SurfCath™ and BLEScath™. Procedural success, number of attempts, and adverse events in neonates receiving MIST via the two catheters were compared using chi-square or Fisher's tests. User experience was described using an ease-of-use scale. # Results Thirty-seven neonates met eligibility criteria; 22 received MIST via SurfCath™, whereas 15 received MIST via BLEScath™. Success rates were 91% in SurfCath™ and 93% in BLEScath™ (P\> 0.994). Failed attempts were lower in SurfCath™ (23%) in comparison to BLEScath™ (33%), but the difference was not statistically significant (P=0.708). Among operators, 90% found SurfCath™ very easy/relatively easy to use compared to 43% of users reflecting the same degree of use with BLEScath™ (P=.021). There was no difference in adverse events. # Conclusion This is the first study in Canada to report MIST with purpose-built catheters. Overall, the success rate was equally high with both catheters. Users subjectively reported higher ease of use with SurfCath™. Commercially available purpose-built catheters should facilitate universal adaptation of the MIST method.https://doi.org/10.29390/001c.77606 |
| spellingShingle | Talib Al Harthy Michael R Miller Orlando daSilva Soume Bhattacharya Purpose built catheters for minimally invasive surfactant therapy: Experience from a Canadian tertiary level neonatal intensive care unit Canadian Journal of Respiratory Therapy |
| title | Purpose built catheters for minimally invasive surfactant therapy: Experience from a Canadian tertiary level neonatal intensive care unit |
| title_full | Purpose built catheters for minimally invasive surfactant therapy: Experience from a Canadian tertiary level neonatal intensive care unit |
| title_fullStr | Purpose built catheters for minimally invasive surfactant therapy: Experience from a Canadian tertiary level neonatal intensive care unit |
| title_full_unstemmed | Purpose built catheters for minimally invasive surfactant therapy: Experience from a Canadian tertiary level neonatal intensive care unit |
| title_short | Purpose built catheters for minimally invasive surfactant therapy: Experience from a Canadian tertiary level neonatal intensive care unit |
| title_sort | purpose built catheters for minimally invasive surfactant therapy experience from a canadian tertiary level neonatal intensive care unit |
| url | https://doi.org/10.29390/001c.77606 |
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