Menopause-Associated Comorbidities and Their Impact on COVID-19 Severity

The Covid-19 pandemic has highlighted the role of biological factors, such as age, sex, and comorbidities, in determining disease severity. Menopause-related changes, including estrogen decline, may increase the severity of symptoms in women, particularly with comorbidities like cardiovascular disea...

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Main Authors: Esseffar Sara, Bellahcen Said, Azizi Ghizlane, Ngadi Hamza, Moumen Abdelmajid
Format: Article
Language:English
Published: EDP Sciences 2025-01-01
Series:E3S Web of Conferences
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Online Access:https://www.e3s-conferences.org/articles/e3sconf/pdf/2025/32/e3sconf_joe52025_01026.pdf
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author Esseffar Sara
Bellahcen Said
Azizi Ghizlane
Ngadi Hamza
Moumen Abdelmajid
author_facet Esseffar Sara
Bellahcen Said
Azizi Ghizlane
Ngadi Hamza
Moumen Abdelmajid
author_sort Esseffar Sara
collection DOAJ
description The Covid-19 pandemic has highlighted the role of biological factors, such as age, sex, and comorbidities, in determining disease severity. Menopause-related changes, including estrogen decline, may increase the severity of symptoms in women, particularly with comorbidities like cardiovascular diseases, hypertension, diabetes, and obesity. This study aims to explore the relationship between the severity of Covid-19 symptoms and menopause-related comorbidities and assess their impact on symptom intensity and recovery duration in menopausal women. A retrospective study was conducted with 50 menopausal women in Nador, Morocco, who had contracted Covid-19. Data were collected through structured interviews and analyzed using SPSS software. Associations between comorbidities and symptom severity were assessed using Chi-Square tests, and recovery times were compared using t-tests. Cardiovascular diseases, diabetes, and high blood pressure were significantly associated with more intense Covid-19 symptoms. Menopausal women with cardiovascular diseases had longer recovery times compared to those without. Obesity showed borderline significance for symptom intensity and recovery time. Comorbidities like cardiovascular disease and diabetes are linked to more severe Covid-19 symptoms and prolonged recovery times in menopausal women. These findings underline the importance of managing comorbid conditions in this population to improve health outcomes.
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spelling doaj-art-92ce2def7b12419a8d71b5dee10ab81d2025-08-20T03:45:04ZengEDP SciencesE3S Web of Conferences2267-12422025-01-016320102610.1051/e3sconf/202563201026e3sconf_joe52025_01026Menopause-Associated Comorbidities and Their Impact on COVID-19 SeverityEsseffar Sara0Bellahcen Said1Azizi Ghizlane2Ngadi Hamza3Moumen Abdelmajid4OLMAN-BGPE, Pluridisciplinary Faculty of Nador, Mohammed first University of OujdaOLMAN-BGPE, Pluridisciplinary Faculty of Nador, Mohammed first University of OujdaOLMAN-BGPE, Pluridisciplinary Faculty of Nador, Mohammed first University of OujdaOLMAN-BGPE, Pluridisciplinary Faculty of Nador, Mohammed first University of OujdaOLMAN-BGPE, Pluridisciplinary Faculty of Nador, Mohammed first University of OujdaThe Covid-19 pandemic has highlighted the role of biological factors, such as age, sex, and comorbidities, in determining disease severity. Menopause-related changes, including estrogen decline, may increase the severity of symptoms in women, particularly with comorbidities like cardiovascular diseases, hypertension, diabetes, and obesity. This study aims to explore the relationship between the severity of Covid-19 symptoms and menopause-related comorbidities and assess their impact on symptom intensity and recovery duration in menopausal women. A retrospective study was conducted with 50 menopausal women in Nador, Morocco, who had contracted Covid-19. Data were collected through structured interviews and analyzed using SPSS software. Associations between comorbidities and symptom severity were assessed using Chi-Square tests, and recovery times were compared using t-tests. Cardiovascular diseases, diabetes, and high blood pressure were significantly associated with more intense Covid-19 symptoms. Menopausal women with cardiovascular diseases had longer recovery times compared to those without. Obesity showed borderline significance for symptom intensity and recovery time. Comorbidities like cardiovascular disease and diabetes are linked to more severe Covid-19 symptoms and prolonged recovery times in menopausal women. These findings underline the importance of managing comorbid conditions in this population to improve health outcomes.https://www.e3s-conferences.org/articles/e3sconf/pdf/2025/32/e3sconf_joe52025_01026.pdfmenopausecovid-19comorbiditiescardiovascular diseasesrecoveryduration
spellingShingle Esseffar Sara
Bellahcen Said
Azizi Ghizlane
Ngadi Hamza
Moumen Abdelmajid
Menopause-Associated Comorbidities and Their Impact on COVID-19 Severity
E3S Web of Conferences
menopause
covid-19
comorbidities
cardiovascular diseases
recovery
duration
title Menopause-Associated Comorbidities and Their Impact on COVID-19 Severity
title_full Menopause-Associated Comorbidities and Their Impact on COVID-19 Severity
title_fullStr Menopause-Associated Comorbidities and Their Impact on COVID-19 Severity
title_full_unstemmed Menopause-Associated Comorbidities and Their Impact on COVID-19 Severity
title_short Menopause-Associated Comorbidities and Their Impact on COVID-19 Severity
title_sort menopause associated comorbidities and their impact on covid 19 severity
topic menopause
covid-19
comorbidities
cardiovascular diseases
recovery
duration
url https://www.e3s-conferences.org/articles/e3sconf/pdf/2025/32/e3sconf_joe52025_01026.pdf
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AT bellahcensaid menopauseassociatedcomorbiditiesandtheirimpactoncovid19severity
AT azizighizlane menopauseassociatedcomorbiditiesandtheirimpactoncovid19severity
AT ngadihamza menopauseassociatedcomorbiditiesandtheirimpactoncovid19severity
AT moumenabdelmajid menopauseassociatedcomorbiditiesandtheirimpactoncovid19severity