Effect of remote ischemic preconditioning on perioperative neurocognitive disorder in elderly patients undergoing major surgery and associated genetic variant analysis: a randomized clinical trial

Effect of remote ischemic preconditioning on perioperative neurocognitive disorder in elderly patients undergoing major surgery and associated genetic variant analysis: a randomized clinical trial

Abstract Objective To investigate whether remote ischemic preconditioning (RIPC) could reduce the incidence of perioperative neurocognitive disorder (PND) in elderly patients undergoing major surgery (> 2 h), to assess the potential of myeloid differentiation factor 2 (MD2) and cystatin C as biom...

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Bibliographic Details
Main Authors: Feifei Xu, Tingting Liu, Huiqing Liu, Jiao Deng, Shan He, Zhihong Lu, Haopeng Zhang, Hailong Dong
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Perioperative Medicine
Subjects:
Remote ischemic preconditioning
PND
Elderly patients
Whole genome sequencing
Online Access:https://doi.org/10.1186/s13741-025-00497-w
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