Single-point multicenter survey of using antimicrobial drugs in the ICUs of Russian multidisciplinary hospitals: results of the Global-PPS 2022 project
Introduction. The marked increase in the resistance of infectious disease pathogens to antimicrobial drugs (AMDs), especially in intensive care units (ICUs), poses a threat to healthcare systems worldwide. This leads to adverse consequences: medical, social and economic. The objective was to evaluat...
Saved in:
| Main Authors: | , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
New Terra Publishing House
2025-04-01
|
| Series: | Вестник анестезиологии и реаниматологии |
| Subjects: | |
| Online Access: | https://www.vair-journal.com/jour/article/view/1200 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850026568978530304 |
|---|---|
| author | Yu. A. Belkova A. A. Kurkova S. A. Rachina R. S. Kozlov E. N. Bochanova E. V. Elokhina S. K. Zyryanov O. V. Ignatenko E. S. Larin G. G. Melkonyan V. M. Mishchenko A. V. Ovsyankin Sh. K. Palyutin O. G. Poplavskaya D. A. Popov U. S. Portnyagina O. V. Reshetko Yu. A. Strezh I. N. Sychev |
| author_facet | Yu. A. Belkova A. A. Kurkova S. A. Rachina R. S. Kozlov E. N. Bochanova E. V. Elokhina S. K. Zyryanov O. V. Ignatenko E. S. Larin G. G. Melkonyan V. M. Mishchenko A. V. Ovsyankin Sh. K. Palyutin O. G. Poplavskaya D. A. Popov U. S. Portnyagina O. V. Reshetko Yu. A. Strezh I. N. Sychev |
| author_sort | Yu. A. Belkova |
| collection | DOAJ |
| description | Introduction. The marked increase in the resistance of infectious disease pathogens to antimicrobial drugs (AMDs), especially in intensive care units (ICUs), poses a threat to healthcare systems worldwide. This leads to adverse consequences: medical, social and economic. The objective was to evaluate the practice of AMDs using in the ICUs of Russian multidisciplinary hospitals based on its compliance with quality indicators.Materials and Methods. Single-point survey of AMDs using was conducted in 37 ICUs of various types in 12 multidisciplinary hospitals in different cities of the Russian Federation (Krasnoyarsk, Moscow (4 centres), Omsk, Saratov, Smolensk (2 centres), Tomsk, Yakutsk and Yaroslavl). The study was conducted in accordance with the protocol of international Global-PPS project from September to December 2022. The object of the study was the medical records of patients who received systemic AMDs for preventive or curative purposes. The practice of AMDs using was studies as well as the assessment of the prescription compliance with the quality indicators.Results. The survey included 501 patients of whom 314 (62.7%) received systemic AMDs. The frequency of AMDs prescription ranged from 24% in cardiac ICUs to 86.9% in surgical ICUs and reached 100% in paediatric departments. The vast majority of drugs were used for therapeutic purposes (74.3%–89.3%) and were prescribed for the treatment of nosocomial infections (71.6% on the average). Carbapenems (20.6%), third-generation cephalosporins (13.1%) and fluoroquinolones (11.6%) prevailed in the structure of prescriptions.Conclusion. The following accuracies in AMDs using were identified during our study: low frequency of etiotropic therapy, inappropriate duration of perioperative antibiotic prophylaxis and relatively low frequency of planning the duration of therapy. These accuracies provide an opportunity to optimize the practice of using drugs of this group in ICUs of hospitals participating in the study. |
| format | Article |
| id | doaj-art-92c8ac94ee404c8b8a46ebc723a33f2c |
| institution | DOAJ |
| issn | 2078-5658 2541-8653 |
| language | Russian |
| publishDate | 2025-04-01 |
| publisher | New Terra Publishing House |
| record_format | Article |
| series | Вестник анестезиологии и реаниматологии |
| spelling | doaj-art-92c8ac94ee404c8b8a46ebc723a33f2c2025-08-20T03:00:31ZrusNew Terra Publishing HouseВестник анестезиологии и реаниматологии2078-56582541-86532025-04-01222263910.24884/2078-5658-2025-22-2-26-39747Single-point multicenter survey of using antimicrobial drugs in the ICUs of Russian multidisciplinary hospitals: results of the Global-PPS 2022 projectYu. A. Belkova0A. A. Kurkova1S. A. Rachina2R. S. Kozlov3E. N. Bochanova4E. V. Elokhina5S. K. Zyryanov6O. V. Ignatenko7E. S. Larin8G. G. Melkonyan9V. M. Mishchenko10A. V. Ovsyankin11Sh. K. Palyutin12O. G. Poplavskaya13D. A. Popov14U. S. Portnyagina15O. V. Reshetko16Yu. A. Strezh17I. N. Sychev18Smolensk State Medical UniversitySmolensk State Medical UniversityI. M. Sechenov First Moscow State Medical UniversitySmolensk State Medical UniversityProf. V. F. Voino-Yasenetsky Krasnoyarsk State Medical UniversityOmsk Regional Clinical HospitalPeoples’ Friendship University of Russia named after Patrice LumumbaS.S. Yudin City Clinical HospitalHospital for War Veterans № 3Hospital for War Veterans № 3Federal Centre of Traumatology, Orthopaedics and EndoprosthesisFederal Centre of Traumatology, Orthopaedics and EndoprosthesisYaroslavl State Medical UniversityTomsk Regional Clinical HospitalA.M. Bakulev National Medical Research Centre for Cardiovascular SurgeryM.K. Ammosov North-Eastern Federal UniversitySaratov State Medical University named after V. I. RazumovskyTomsk Regional Clinical HospitalRussian Medical Academy of Continuing Professional EducationIntroduction. The marked increase in the resistance of infectious disease pathogens to antimicrobial drugs (AMDs), especially in intensive care units (ICUs), poses a threat to healthcare systems worldwide. This leads to adverse consequences: medical, social and economic. The objective was to evaluate the practice of AMDs using in the ICUs of Russian multidisciplinary hospitals based on its compliance with quality indicators.Materials and Methods. Single-point survey of AMDs using was conducted in 37 ICUs of various types in 12 multidisciplinary hospitals in different cities of the Russian Federation (Krasnoyarsk, Moscow (4 centres), Omsk, Saratov, Smolensk (2 centres), Tomsk, Yakutsk and Yaroslavl). The study was conducted in accordance with the protocol of international Global-PPS project from September to December 2022. The object of the study was the medical records of patients who received systemic AMDs for preventive or curative purposes. The practice of AMDs using was studies as well as the assessment of the prescription compliance with the quality indicators.Results. The survey included 501 patients of whom 314 (62.7%) received systemic AMDs. The frequency of AMDs prescription ranged from 24% in cardiac ICUs to 86.9% in surgical ICUs and reached 100% in paediatric departments. The vast majority of drugs were used for therapeutic purposes (74.3%–89.3%) and were prescribed for the treatment of nosocomial infections (71.6% on the average). Carbapenems (20.6%), third-generation cephalosporins (13.1%) and fluoroquinolones (11.6%) prevailed in the structure of prescriptions.Conclusion. The following accuracies in AMDs using were identified during our study: low frequency of etiotropic therapy, inappropriate duration of perioperative antibiotic prophylaxis and relatively low frequency of planning the duration of therapy. These accuracies provide an opportunity to optimize the practice of using drugs of this group in ICUs of hospitals participating in the study.https://www.vair-journal.com/jour/article/view/1200single-point surveyicuintensive careantibioticantimicrobial drug |
| spellingShingle | Yu. A. Belkova A. A. Kurkova S. A. Rachina R. S. Kozlov E. N. Bochanova E. V. Elokhina S. K. Zyryanov O. V. Ignatenko E. S. Larin G. G. Melkonyan V. M. Mishchenko A. V. Ovsyankin Sh. K. Palyutin O. G. Poplavskaya D. A. Popov U. S. Portnyagina O. V. Reshetko Yu. A. Strezh I. N. Sychev Single-point multicenter survey of using antimicrobial drugs in the ICUs of Russian multidisciplinary hospitals: results of the Global-PPS 2022 project Вестник анестезиологии и реаниматологии single-point survey icu intensive care antibiotic antimicrobial drug |
| title | Single-point multicenter survey of using antimicrobial drugs in the ICUs of Russian multidisciplinary hospitals: results of the Global-PPS 2022 project |
| title_full | Single-point multicenter survey of using antimicrobial drugs in the ICUs of Russian multidisciplinary hospitals: results of the Global-PPS 2022 project |
| title_fullStr | Single-point multicenter survey of using antimicrobial drugs in the ICUs of Russian multidisciplinary hospitals: results of the Global-PPS 2022 project |
| title_full_unstemmed | Single-point multicenter survey of using antimicrobial drugs in the ICUs of Russian multidisciplinary hospitals: results of the Global-PPS 2022 project |
| title_short | Single-point multicenter survey of using antimicrobial drugs in the ICUs of Russian multidisciplinary hospitals: results of the Global-PPS 2022 project |
| title_sort | single point multicenter survey of using antimicrobial drugs in the icus of russian multidisciplinary hospitals results of the global pps 2022 project |
| topic | single-point survey icu intensive care antibiotic antimicrobial drug |
| url | https://www.vair-journal.com/jour/article/view/1200 |
| work_keys_str_mv | AT yuabelkova singlepointmulticentersurveyofusingantimicrobialdrugsintheicusofrussianmultidisciplinaryhospitalsresultsoftheglobalpps2022project AT aakurkova singlepointmulticentersurveyofusingantimicrobialdrugsintheicusofrussianmultidisciplinaryhospitalsresultsoftheglobalpps2022project AT sarachina singlepointmulticentersurveyofusingantimicrobialdrugsintheicusofrussianmultidisciplinaryhospitalsresultsoftheglobalpps2022project AT rskozlov singlepointmulticentersurveyofusingantimicrobialdrugsintheicusofrussianmultidisciplinaryhospitalsresultsoftheglobalpps2022project AT enbochanova singlepointmulticentersurveyofusingantimicrobialdrugsintheicusofrussianmultidisciplinaryhospitalsresultsoftheglobalpps2022project AT evelokhina singlepointmulticentersurveyofusingantimicrobialdrugsintheicusofrussianmultidisciplinaryhospitalsresultsoftheglobalpps2022project AT skzyryanov singlepointmulticentersurveyofusingantimicrobialdrugsintheicusofrussianmultidisciplinaryhospitalsresultsoftheglobalpps2022project AT ovignatenko singlepointmulticentersurveyofusingantimicrobialdrugsintheicusofrussianmultidisciplinaryhospitalsresultsoftheglobalpps2022project AT eslarin singlepointmulticentersurveyofusingantimicrobialdrugsintheicusofrussianmultidisciplinaryhospitalsresultsoftheglobalpps2022project AT ggmelkonyan singlepointmulticentersurveyofusingantimicrobialdrugsintheicusofrussianmultidisciplinaryhospitalsresultsoftheglobalpps2022project AT vmmishchenko singlepointmulticentersurveyofusingantimicrobialdrugsintheicusofrussianmultidisciplinaryhospitalsresultsoftheglobalpps2022project AT avovsyankin singlepointmulticentersurveyofusingantimicrobialdrugsintheicusofrussianmultidisciplinaryhospitalsresultsoftheglobalpps2022project AT shkpalyutin singlepointmulticentersurveyofusingantimicrobialdrugsintheicusofrussianmultidisciplinaryhospitalsresultsoftheglobalpps2022project AT ogpoplavskaya singlepointmulticentersurveyofusingantimicrobialdrugsintheicusofrussianmultidisciplinaryhospitalsresultsoftheglobalpps2022project AT dapopov singlepointmulticentersurveyofusingantimicrobialdrugsintheicusofrussianmultidisciplinaryhospitalsresultsoftheglobalpps2022project AT usportnyagina singlepointmulticentersurveyofusingantimicrobialdrugsintheicusofrussianmultidisciplinaryhospitalsresultsoftheglobalpps2022project AT ovreshetko singlepointmulticentersurveyofusingantimicrobialdrugsintheicusofrussianmultidisciplinaryhospitalsresultsoftheglobalpps2022project AT yuastrezh singlepointmulticentersurveyofusingantimicrobialdrugsintheicusofrussianmultidisciplinaryhospitalsresultsoftheglobalpps2022project AT insychev singlepointmulticentersurveyofusingantimicrobialdrugsintheicusofrussianmultidisciplinaryhospitalsresultsoftheglobalpps2022project |