POTENTIAL OF ANGIOTENSIN-CONVERTING ENZYME INHIBITORS IN THE TREATMENT OF PATIENTS WITH ARTERIAL HYPERTENSION AND CORONARY HEART DISEASE

For the last 30 years, angiotensin-converting enzyme (ACE) inhibitors have been playing a key role in the management of arterial hypertension (AH) and related cardiovascular disease. This review discusses the mechanisms of action and organo-protective effects of ACE inhibitors. Enalapril is the most...

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Main Authors: A. G. Evdokimova, V. V. Evdokimov
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 2013-02-01
Series:Кардиоваскулярная терапия и профилактика
Subjects:
Online Access:https://cardiovascular.elpub.ru/jour/article/view/123
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author A. G. Evdokimova
V. V. Evdokimov
author_facet A. G. Evdokimova
V. V. Evdokimov
author_sort A. G. Evdokimova
collection DOAJ
description For the last 30 years, angiotensin-converting enzyme (ACE) inhibitors have been playing a key role in the management of arterial hypertension (AH) and related cardiovascular disease. This review discusses the mechanisms of action and organo-protective effects of ACE inhibitors. Enalapril is the most extensively studied and widely used in the international clinical practice ACE inhibitor. The authors analyse the results of the studies on enalapril therapy in AH, coronary heart disease (CHD), chronic heart failure, metabolic syndrome, and postmenopause. It has been demonstrated that the combination antihypertensive therapy with a β-adrenoblocker nebivolol, enalapril, and hydrochlorothiazide (such as Berlipril® Plus) is safe and effective in patients with AH and CHD.
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institution Kabale University
issn 1728-8800
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language Russian
publishDate 2013-02-01
publisher «SILICEA-POLIGRAF» LLC
record_format Article
series Кардиоваскулярная терапия и профилактика
spelling doaj-art-92c2a48d54e9430cadbc96cbd0f58d092025-08-20T03:35:47Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252013-02-01121808710.15829/1728-8800-2013-1-80-87123POTENTIAL OF ANGIOTENSIN-CONVERTING ENZYME INHIBITORS IN THE TREATMENT OF PATIENTS WITH ARTERIAL HYPERTENSION AND CORONARY HEART DISEASEA. G. Evdokimova0V. V. Evdokimov1A.I. Evdokimov Moscow State Medico-Stomatological University, MoscowA.I. Evdokimov Moscow State Medico-Stomatological University, MoscowFor the last 30 years, angiotensin-converting enzyme (ACE) inhibitors have been playing a key role in the management of arterial hypertension (AH) and related cardiovascular disease. This review discusses the mechanisms of action and organo-protective effects of ACE inhibitors. Enalapril is the most extensively studied and widely used in the international clinical practice ACE inhibitor. The authors analyse the results of the studies on enalapril therapy in AH, coronary heart disease (CHD), chronic heart failure, metabolic syndrome, and postmenopause. It has been demonstrated that the combination antihypertensive therapy with a β-adrenoblocker nebivolol, enalapril, and hydrochlorothiazide (such as Berlipril® Plus) is safe and effective in patients with AH and CHD.https://cardiovascular.elpub.ru/jour/article/view/123arterial hypertensioncoronary heart diseaseangiotensinconverting enzyme inhibitorsberlipril®berlipril® plus
spellingShingle A. G. Evdokimova
V. V. Evdokimov
POTENTIAL OF ANGIOTENSIN-CONVERTING ENZYME INHIBITORS IN THE TREATMENT OF PATIENTS WITH ARTERIAL HYPERTENSION AND CORONARY HEART DISEASE
Кардиоваскулярная терапия и профилактика
arterial hypertension
coronary heart disease
angiotensinconverting enzyme inhibitors
berlipril®
berlipril® plus
title POTENTIAL OF ANGIOTENSIN-CONVERTING ENZYME INHIBITORS IN THE TREATMENT OF PATIENTS WITH ARTERIAL HYPERTENSION AND CORONARY HEART DISEASE
title_full POTENTIAL OF ANGIOTENSIN-CONVERTING ENZYME INHIBITORS IN THE TREATMENT OF PATIENTS WITH ARTERIAL HYPERTENSION AND CORONARY HEART DISEASE
title_fullStr POTENTIAL OF ANGIOTENSIN-CONVERTING ENZYME INHIBITORS IN THE TREATMENT OF PATIENTS WITH ARTERIAL HYPERTENSION AND CORONARY HEART DISEASE
title_full_unstemmed POTENTIAL OF ANGIOTENSIN-CONVERTING ENZYME INHIBITORS IN THE TREATMENT OF PATIENTS WITH ARTERIAL HYPERTENSION AND CORONARY HEART DISEASE
title_short POTENTIAL OF ANGIOTENSIN-CONVERTING ENZYME INHIBITORS IN THE TREATMENT OF PATIENTS WITH ARTERIAL HYPERTENSION AND CORONARY HEART DISEASE
title_sort potential of angiotensin converting enzyme inhibitors in the treatment of patients with arterial hypertension and coronary heart disease
topic arterial hypertension
coronary heart disease
angiotensinconverting enzyme inhibitors
berlipril®
berlipril® plus
url https://cardiovascular.elpub.ru/jour/article/view/123
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AT vvevdokimov potentialofangiotensinconvertingenzymeinhibitorsinthetreatmentofpatientswitharterialhypertensionandcoronaryheartdisease