Características clínico-epidemiológicas de brote de ehrlichiosis en Centro Médico Olanchano de Juticalpa, Olancho 2023
Introduction: Ehrlichiosis is a zoonotic disease, caused by Ehrlichia, a pleomorphic obligate intracellular Gram-negative Gram-negative bacterium, transmitted to humans throughtick bites. Objective: To determine the clinical-epidemiological characteristics of the outbreak of eh...
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Colegio Médico de Honduras
2025-06-01
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| author | Carlos Mejía Irías Jaqueline Hernández Posadas Valeria Zapata Nelson Mercadal |
| author_facet | Carlos Mejía Irías Jaqueline Hernández Posadas Valeria Zapata Nelson Mercadal |
| author_sort | Carlos Mejía Irías |
| collection | DOAJ |
| description | Introduction: Ehrlichiosis is a zoonotic disease, caused by Ehrlichia, a pleomorphic obligate intracellular Gram-negative Gram-negative bacterium, transmitted to humans throughtick bites. Objective: To determine the clinical-epidemiological characteristics of the outbreak of ehrlichiosis registered in Centro Médico Olanchano de Juticalpa, Honduras, 2023. Methods:Descriptive, retrospective study, 134 patient files were reviewed from patients attending the Internal Medicine outpatient clinic of the Centro Médico Olanchano; 103 met inclusion/exclusion criteria. Diagnosis was made by identification of morulae in peripheral blood smears. Results: Of the patients with ehrlichiosis, 75.7% (78) were female, mean age 58 years. The months with the highest number of Ehrlichia positive cases were April, May and June: 71.8% (74). Clinical manifestations were: fever 35.9% (37), fatigue 27.1% (28) and chills 17.4% (18). One case had a neurological complication of Guillain-Barré syndrome, representing 0.9% (1) at . Only 6.8% (7) recalled being bitten by ticks. 100% received doxycycline; 81.5% (84) had no morulae detected and 18.4% (19) had persistence in the control peripheral blood smear. Discussion: The clinical-epidemiological characteristics of patients with ehrlichiosis showedseasonal behaviour, affecting females, age 58 years. Clinical manifestations were fever, fatigue and chills. Treatment with doxycycline was effective in most cases, and a group of patients required alternative treatment with rifampicin, achieving microbiological eradication. |
| format | Article |
| id | doaj-art-92c297c0fdb4495197c49ffe0b2024d0 |
| institution | DOAJ |
| issn | 0375-1112 1995-7068 |
| language | Spanish |
| publishDate | 2025-06-01 |
| publisher | Colegio Médico de Honduras |
| record_format | Article |
| series | Revista Médica Hondureña |
| spelling | doaj-art-92c297c0fdb4495197c49ffe0b2024d02025-08-20T02:48:06ZspaColegio Médico de HondurasRevista Médica Hondureña0375-11121995-70682025-06-01931253010.5377/rmh.v93i1.20639Características clínico-epidemiológicas de brote de ehrlichiosis en Centro Médico Olanchano de Juticalpa, Olancho 2023Carlos Mejía Irías0https://orcid.org/0009-0004-2377-329XJaqueline Hernández Posadas1https://orcid.org/0000-0003-2572-4403Valeria Zapata2https://orcid.org/0009-0008-0941-6607Nelson Mercadal3https://orcid.org/0009-0007-7446-507XCentro Médico Olanchano, Departamento de Medicina Interna; Juticalpa, Honduras.Centro Médico Olanchano, Departamento de Emergencia; Juticalpa, Honduras.Centro Médico Olanchano, Departamento de Emergencia; Juticalpa, Honduras.Centro Médico Olanchano, Departamento de Medicina Interna; Juticalpa, Honduras. Introduction: Ehrlichiosis is a zoonotic disease, caused by Ehrlichia, a pleomorphic obligate intracellular Gram-negative Gram-negative bacterium, transmitted to humans throughtick bites. Objective: To determine the clinical-epidemiological characteristics of the outbreak of ehrlichiosis registered in Centro Médico Olanchano de Juticalpa, Honduras, 2023. Methods:Descriptive, retrospective study, 134 patient files were reviewed from patients attending the Internal Medicine outpatient clinic of the Centro Médico Olanchano; 103 met inclusion/exclusion criteria. Diagnosis was made by identification of morulae in peripheral blood smears. Results: Of the patients with ehrlichiosis, 75.7% (78) were female, mean age 58 years. The months with the highest number of Ehrlichia positive cases were April, May and June: 71.8% (74). Clinical manifestations were: fever 35.9% (37), fatigue 27.1% (28) and chills 17.4% (18). One case had a neurological complication of Guillain-Barré syndrome, representing 0.9% (1) at . Only 6.8% (7) recalled being bitten by ticks. 100% received doxycycline; 81.5% (84) had no morulae detected and 18.4% (19) had persistence in the control peripheral blood smear. Discussion: The clinical-epidemiological characteristics of patients with ehrlichiosis showedseasonal behaviour, affecting females, age 58 years. Clinical manifestations were fever, fatigue and chills. Treatment with doxycycline was effective in most cases, and a group of patients required alternative treatment with rifampicin, achieving microbiological eradication.https://www.camjol.info/index.php/RMH/article/view/20639ehrlichiosisehrlichia infectionhuman ehrlichiosisdisease outbreak |
| spellingShingle | Carlos Mejía Irías Jaqueline Hernández Posadas Valeria Zapata Nelson Mercadal Características clínico-epidemiológicas de brote de ehrlichiosis en Centro Médico Olanchano de Juticalpa, Olancho 2023 Revista Médica Hondureña ehrlichiosis ehrlichia infection human ehrlichiosis disease outbreak |
| title | Características clínico-epidemiológicas de brote de ehrlichiosis en Centro Médico Olanchano de Juticalpa, Olancho 2023 |
| title_full | Características clínico-epidemiológicas de brote de ehrlichiosis en Centro Médico Olanchano de Juticalpa, Olancho 2023 |
| title_fullStr | Características clínico-epidemiológicas de brote de ehrlichiosis en Centro Médico Olanchano de Juticalpa, Olancho 2023 |
| title_full_unstemmed | Características clínico-epidemiológicas de brote de ehrlichiosis en Centro Médico Olanchano de Juticalpa, Olancho 2023 |
| title_short | Características clínico-epidemiológicas de brote de ehrlichiosis en Centro Médico Olanchano de Juticalpa, Olancho 2023 |
| title_sort | caracteristicas clinico epidemiologicas de brote de ehrlichiosis en centro medico olanchano de juticalpa olancho 2023 |
| topic | ehrlichiosis ehrlichia infection human ehrlichiosis disease outbreak |
| url | https://www.camjol.info/index.php/RMH/article/view/20639 |
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