Discordance of 3rd and 4th generation QuantiFERON-TB Gold assays by pregnancy stages in India

Discordance of 3rd and 4th generation QuantiFERON-TB Gold assays by pregnancy stages in India

Background: Pregnancy and HIV affect CD4+ T lymphocytes and impact performance of QuantiFERON-TB Gold (QFT). We compared the results of QFT with QuantiFERON-TB Gold Plus (QFT-Plus), which also measures CD8+ responses to TB antigens, during pregnancy and postpartum. Methods: We screened 516 pregnant...

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Bibliographic Details
Main Authors: Vandana Kulkarni, Mallika Alexander, Ramesh Bhosale, Divyashri Jain, Prasad Deshpande, Emily Shira Gitlin, Arthi Vaidyanathan, Andrea Chalem, Shilpa Naik, Nikhil Gupte, Neelu Nawani, Amita Gupta, Jyoti Mathad
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Journal of Clinical Tuberculosis and Other Mycobacterial Diseases
Subjects:
IGRA
TBI
Pregnancy
HIV
QFT-Plus
Online Access:http://www.sciencedirect.com/science/article/pii/S2405579424000913
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