Gut microbiota and endometrial cancer: research progress on the pathogenesis and application
As one of the three major malignant tumors in women, the morbidity of endometrial cancer is second only to that of cervical cancer and is increasing yearly. Its etiological mechanism is not clear, and the risk factors are numerous and common and are closely related to obesity, hypertension, diabetes...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2025-12-01
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| Series: | Annals of Medicine |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/07853890.2025.2451766 |
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| author | Weiqin Zheng Xiaowen Lin Huixin Chen Ziling Yang Han Zhao Shibo Li Tao Song Yuhui Sun |
| author_facet | Weiqin Zheng Xiaowen Lin Huixin Chen Ziling Yang Han Zhao Shibo Li Tao Song Yuhui Sun |
| author_sort | Weiqin Zheng |
| collection | DOAJ |
| description | As one of the three major malignant tumors in women, the morbidity of endometrial cancer is second only to that of cervical cancer and is increasing yearly. Its etiological mechanism is not clear, and the risk factors are numerous and common and are closely related to obesity, hypertension, diabetes, etc. The gut microbiota has many strains, which play a considerable part in normal digestion and absorption in the human body and the regulation of the immune response. In the last few years, research on the gut microbiota has been unprecedentedly popular, and it has been confirmed that the gut microbiota closely correlates with the occurrence and development of all kinds of benign and malignant diseases. In this article, the effects of the gut microbiota and its metabolites on the occurrence and development of endometrial cancer is reviewed, and its application in the prevention, diagnosis and treatment of endometrial cancer is explored. |
| format | Article |
| id | doaj-art-92b592be536d46d1b3881235dbbf2420 |
| institution | Kabale University |
| issn | 0785-3890 1365-2060 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Annals of Medicine |
| spelling | doaj-art-92b592be536d46d1b3881235dbbf24202025-01-15T08:48:48ZengTaylor & Francis GroupAnnals of Medicine0785-38901365-20602025-12-0157110.1080/07853890.2025.2451766Gut microbiota and endometrial cancer: research progress on the pathogenesis and applicationWeiqin Zheng0Xiaowen Lin1Huixin Chen2Ziling Yang3Han Zhao4Shibo Li5Tao Song6Yuhui Sun7Department of Gynecology, the First Affiliated Hospital of Harbin Medical University, Harbin, ChinaDepartment of Gynecology, the First Affiliated Hospital of Harbin Medical University, Harbin, ChinaDepartment of Gynecology, the First Affiliated Hospital of Harbin Medical University, Harbin, ChinaDepartment of Gynecology, the First Affiliated Hospital of Harbin Medical University, Harbin, ChinaDepartment of Gynecology, the First Affiliated Hospital of Harbin Medical University, Harbin, ChinaDepartment of Gynecology, the First Affiliated Hospital of Harbin Medical University, Harbin, ChinaDepartment of Cardiology, the First Affiliated Hospital of Harbin Medical University, Harbin, ChinaDepartment of Gynecology, the First Affiliated Hospital of Harbin Medical University, Harbin, ChinaAs one of the three major malignant tumors in women, the morbidity of endometrial cancer is second only to that of cervical cancer and is increasing yearly. Its etiological mechanism is not clear, and the risk factors are numerous and common and are closely related to obesity, hypertension, diabetes, etc. The gut microbiota has many strains, which play a considerable part in normal digestion and absorption in the human body and the regulation of the immune response. In the last few years, research on the gut microbiota has been unprecedentedly popular, and it has been confirmed that the gut microbiota closely correlates with the occurrence and development of all kinds of benign and malignant diseases. In this article, the effects of the gut microbiota and its metabolites on the occurrence and development of endometrial cancer is reviewed, and its application in the prevention, diagnosis and treatment of endometrial cancer is explored.https://www.tandfonline.com/doi/10.1080/07853890.2025.2451766Gut microbiotaendometrial cancerestrogenhypertensioninsulin resistancebiomarker |
| spellingShingle | Weiqin Zheng Xiaowen Lin Huixin Chen Ziling Yang Han Zhao Shibo Li Tao Song Yuhui Sun Gut microbiota and endometrial cancer: research progress on the pathogenesis and application Annals of Medicine Gut microbiota endometrial cancer estrogen hypertension insulin resistance biomarker |
| title | Gut microbiota and endometrial cancer: research progress on the pathogenesis and application |
| title_full | Gut microbiota and endometrial cancer: research progress on the pathogenesis and application |
| title_fullStr | Gut microbiota and endometrial cancer: research progress on the pathogenesis and application |
| title_full_unstemmed | Gut microbiota and endometrial cancer: research progress on the pathogenesis and application |
| title_short | Gut microbiota and endometrial cancer: research progress on the pathogenesis and application |
| title_sort | gut microbiota and endometrial cancer research progress on the pathogenesis and application |
| topic | Gut microbiota endometrial cancer estrogen hypertension insulin resistance biomarker |
| url | https://www.tandfonline.com/doi/10.1080/07853890.2025.2451766 |
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