Effect of simvastatin on expression of Interleukins 6 & 10 and Matrix Metalloproteinase: 9 when used as an intracanal medicament in teeth with symptomatic apical periodontitis-a triple blind randomized controlled trial

Effect of simvastatin on expression of Interleukins 6 & 10 and Matrix Metalloproteinase: 9 when used as an intracanal medicament in teeth with symptomatic apical periodontitis-a triple blind randomized controlled trial

Abstract Background The objective of this prospective, triple-blind, randomized clinical controlled trial is to investigate and compare the expressions of interleukin-6 (IL-6), interleukin-10 (IL-10), and matrix metalloproteinase-9 (MMP-9) in the periapical tissues of teeth with symptomatic apical p...

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Bibliographic Details
Main Authors: Nikhil Harikrishnan, Ravi Kumar Nesamani, S. Aysha Sherin, Kavitha Sanjeev, Mahalaxmi Sekar
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Journal of Translational Medicine
Subjects:
Ca(OH)2
Interleukin
Intracanal medicament
Matrix metalloproteinase
Periapical periodontitis
Simvastatin
Online Access:https://doi.org/10.1186/s12967-025-06579-z
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