Novel Whey Fermented Beverage Enriched with a Mixture of Juice Concentrates: Evaluation of Antimicrobial, Antioxidant, and Angiotensin I Converting Enzyme Inhibitory (ACE) Activities Before and After Simulated Gastrointestinal Digestion

This study explored the development of a novel whey-based fermented beverage enriched with juice concentrates and health-promoting ingredients, emphasizing its bioactive properties. The formulation included whey protein isolate (5%), juice concentrates (10% apple, raspberry, and cranberry), and inul...

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Bibliographic Details
Main Authors: Paschalia Kotsaki, Maria Aspri, Photis Papademas
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Microorganisms
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Online Access:https://www.mdpi.com/2076-2607/13/7/1490
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Summary:This study explored the development of a novel whey-based fermented beverage enriched with juice concentrates and health-promoting ingredients, emphasizing its bioactive properties. The formulation included whey protein isolate (5%), juice concentrates (10% apple, raspberry, and cranberry), and inulin (4%). Fermentation was carried out with the following strains: <i>Lacticaseibacillus rhamnosus</i> (LGG), <i>Lacticaseibacillus casei</i> (431), and <i>Lactobacillus helveticus</i> (R0052) at 2%. Antimicrobial activity was evaluated against pathogens including <i>Listeria monocytogenes</i> (strains 33423 and 33413), <i>Staphylococcus aureus</i> (113 and Newman), <i>Bacillus cereus</i> (DPC 6089), <i>Escherichia coli</i> (NCTC 9001), and <i>Salmonella Enteritidis</i> (NCTC 6676). Antioxidant capacity was measured using 2,2-Diphenyl-1-picrylhydrazylradical (DPPH) and Ferric Reducing Antioxidant Power (FRAP) assays, and angiotensin-converting enzyme (ACE) inhibitory activity was assessed. All bioactivities were found to be high in fermented whey beverage and a further significant increase was observed after simulated gastrointestinal digestion. This fruit-flavored whey beverage demonstrated notable antimicrobial and antioxidant activities, highlighting its potential for functional food applications aimed at combating harmful bacteria and oxidative stress.
ISSN:2076-2607